Vivet Therapeutics Announces 2 Abstracts Accepted for Oral Presentation at 2019 American Society of Gene and Cell Therapy Annual Meeting
Vivet Therapeutics (“Vivet”), a privately held gene therapy biotech company dedicated to developing gene therapy treatments for inherited liver disorders with high unmet medical need, today announced that new data from its lead development program, VTX-801 a novel investigational gene therapy for WD, and VTX-803, Vivet’ novel therapeutic in development for the treatment of PFIC3, have been accepted for oral presentation during the ASGCT 22nd Annual Meeting, April 29 - May 2, 2019 in Washington, D.C., USA.
Dr. Gloria González-Aseguinolaza, Vivet Therapeutics CSO & Head of the
Gene Therapy Dept. at FIMA will present data from a recently completed
study, validating in WD mice the use of fecal excretion of IV-injected 64
as a pharmacodynamic endpoint in the VTX-801 Phase I/II trial currently
under preparation. These data are the first demonstration of copper
homeostasis restoration with 64
Copper in an animal model of
WD through the delivery of a single, intravenous administration of AAV.
Title: Preclinical Validation of 64 Copper as a Translational Tool for Evaluating the Pharmacodynamics of VTX-801 Gene Therapy in Wilson disease (Tuesday April 30 at 3:30-3:45pm / Room: Heights Courtyard 2)
New findings from recently completed preclinical study of VTX-803 will be presented by Dr. Nicholas D. Weber, Research Scientist at Vivet. Dr Weber will present a new animal proof of concept study for VTX-803, one of Vivet’s portfolio indications: “AAV Expressing MDR3 (VTX-803) Mediates the Correction of Progressive Familial Intrahepatic Cholestasis Type 3 (PFIC3) in a Clinically Relevant Mouse Model ” (Tuesday April 30 at 4:15-4:30pm / Room: Heights Courtyard 1). These data expand and confirm earlier observations.
The abstracts listed above has been accepted for an Oral Presentation and can be found online at: https://www.asgct.org/global/documents/asgct19_abstracts_-final
Vivet Therapeutics will also be presenting during the Wilson Disease Association (WDA) 2019 annual conference (May 3-4 / New York, USA) and at the Wilson Aarhus 2019 symposium (May 9-12 / Aarhus, Denmark).
About Vivet Therapeutics
Vivet Therapeutics is an emerging biotechnology company developing novel gene therapy treatments for rare, inherited metabolic diseases.
Vivet is building a diversified gene therapy pipeline based on novel adeno-associated virus (AAV) technologies developed through its partnerships with, and exclusive licenses from, the Fundación para la Investigación Médica Aplicada (FIMA), a not-for-profit foundation at the Centro de Investigación Medica Aplicada, University of Navarra based in Pamplona, Spain.
Vivet’s lead program, VTX-801, is a novel investigational gene therapy for Wilson disease which has been granted Orphan Drug Designation by the Food and Drug Administration and the European Commission.
Vivet is supported by international life science investors. For more information please visit us on www.vivet-therapeutics.com and follow us on Twitter at @Vivet_tx and LinkedIn.
Media & Investor contact:
Information om Business Wire
101 California Street, 20th Floor
CA 94111 San Francisco
Følg pressemeddelelser fra Business Wire
Skriv dig op her, og modtag pressemeddelelser på e-mail. Indtast din e-mail, klik på abonner, og følg instruktionerne i den udsendte e-mail.
Flere pressemeddelelser fra Business Wire
PA-KNOPP-BIOSCIENCES24.5.2019 16:02:05 CEST | Pressemeddelelse
Knopp Biosciences Presents Positive Preclinical Data for Lead Neonatal Epilepsy Drug Candidate at 2019 Antiepileptic Drug and Device Trials XV Conference
NIPA24.5.2019 12:22:09 CEST | Pressemeddelelse
Accelerate Your Business in South Korea Through 2019 K-Startup Grand Challenge
IPSEN24.5.2019 07:02:07 CEST | Pressemeddelelse
New Investigational Clinical Data for Ipsen’s Oncology Products in 11 Solid Tumor Types to Be Presented at 2019 ASCO Annual Meeting
POSIFLEX-GROUP24.5.2019 03:02:05 CEST | Pressemeddelelse
The Posiflex Group Showcases an Ecosystem of Connected Solution Endpoints with IoT Remote Monitoring at Computex 2019
CA-ANDERSEN-TAX23.5.2019 22:49:12 CEST | Pressemeddelelse
Andersen Global udvider lokaliteter i Storbritannien
VA-CTA23.5.2019 22:02:10 CEST | Pressemeddelelse
Audi China President Thomas Owsianski to Keynote at CES Asia 2019
I vores nyhedsrum kan du læse alle vores pressemeddelelser, tilgå materiale i form af billeder og dokumenter samt finde vores kontaktoplysninger.Besøg vores nyhedsrum