PHILOGEN
Philogen S.p.A., a privately owned biotechnology company today announced a collaboration and license agreement with Boehringer Ingelheim to discover and optimize novel small molecule-based therapeutics using Philochem’s proprietary Encoded Self-Assembling Chemical (ESAC) Library Technology platform.
“We are extremely pleased to announce a new collaboration with Boehringer Ingelheim, a very innovative pharmaceutical company with a long tradition both in the field of therapeutic proteins and of small-molecule pharmaceuticals. After the initial clinical collaboration with Boehringer Ingelheim in the immune-oncology space announced in 2016, this second partnership underlines the good relationship between the two companies. We are both committed to the creation of new pharmaceutical agents, which may help treat serious unmet medical needs and provide a benefit to patients. ESAC technology is ideally suited for the identification of synergistic chemical fragments, which recognize adjacent binding sites on the surface of the target protein of interest. We are confident that ESAC technology will facilitate hit and lead discovery activities, complementing the strong Medicinal Chemistry technologies already established at Boehringer Ingelheim”, commented Prof. Dario Neri, co-founder and President of the Scientific Advisory Board of Philogen.
ESAC technology represents an innovative proprietary methodology for the construction and screening of DNA-encoded chemical libraries of unprecedented size and quality. ESAC libraries, which are generated by the combinatorial self-assembly of encoded libraries of very high purity, are different compared to conventional single-pharmacophore chemical libraries.
Darryl McConnell, Vice President and Head, Boehringer Ingelheim Research Site Austria, said, “We are very excited about the opportunity to apply Philochem’s DNA-encoded library technology to drugging intractable proteins. We believe that Philochem’s unique chemistry combined with Boehringer Ingelheim’s capabilities in discovering novel drugs could accelerate the optimization of chemical starting points to potent drug candidates”.
No financial details of the agreement were released.
About the Philogen group
Philogen is a Swiss-Italian clinical-stage company engaged in the discovery and development of novel pharmaceutical and biopharmaceutical products. Philogen’s strategy is to deliver bioactive agents, for example cytokines or drugs, to the site of disease using antibodies and other ligands that specifically and efficiently target stromal antigens. This technology has generated a strong proprietary pipeline of clinical-stage products and also pre-clinical compounds in an array of disease indications. Philogen is headquartered in Siena, Italy, and has research activities at its subsidiary company Philochem in Zürich, Switzerland. Philogen is independently owned, and has signed agreements with several major pharmaceutical companies. For more information please visit www.philogen.com .
About Philochem’s ESAC platform and DNA-Encoded Chemistry technology
The proprietary ESAC platform and DNA-Encoded Chemistry technology were developed by Philochem scientists in collaboration with the group of Prof. Dario Neri at ETH Zurich during the past decade. These two powerful and complementary discovery technologies allow to screen up to billions small molecules and to further optimize the hit compounds in a fully automatic, DNA-tagged, fragment-based drug discovery manner.
View source version on businesswire.com: http://www.businesswire.com/news/home/20170720005062/en/
Contact:
Philogen
Monica Patti
monica.patti@philogen.com
Link:
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
FLATEXDEGIRO-AG25.4.2024 20:20:33 CEST | Press release
flatexDEGIRO Starts Into Expected Record Year 2024 With a Jump in Revenues and Earnings
CA-OPENGATE-CAPITAL25.4.2024 19:15:32 CEST | Press release
OpenGate Capital Completes Sale of SMAC
FARCANA25.4.2024 17:41:30 CEST | Press release
Farcana Announces Gateway: Showdown - Playtest Kicks Off April 30th, with a 1,000,000 $FAR token prize pool!
ANTOGNOLLA25.4.2024 16:40:29 CEST | Press release
Antognolla at International Hospitality Investment Forum: Growing Interest in the Italian Market from Hotel Operators and Investors
CA-LASERFICHE25.4.2024 16:31:29 CEST | Press release
Digital Transformation’s Next Era: Generative AI and Laserfiche 12 at 2024 Empower Conference
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom