MERCK
Merck, a leading science and technology company, today announced a mutual decision with GSK to terminate their agreement on bintrafusp alfa, effective September 30, 2021.
The decision is based on the clinical trial data generated to date, most notably the previously reported results from the INTR@PID Lung 037 study, which did not replicate the encouraging data observed in earlier studies. Based on the data generated during the agreement, no milestone payments were made by GSK and no future milestone obligations remain.
The INTR@PID clinical program sought to validate the potential of the novel mechanism of simultaneously blocking TGF-ß and PD-L1, with the ambition to improve outcomes for patients with difficult-to-treat cancers. Given the extent of the clinical program, Merck will deepen its scientific leadership in the field and interrogate the data leveraging the power of advanced analytics. The important insights this program has yielded about the biology of TGF-β will inform the collective understanding of this pathway.
Merck is a science-led organization dedicated to delivering transformative medicines with the goal of making a meaningful difference in the lives of people affected by cancer. Our oncology research efforts, comprised of 10 ongoing development programs, aim to leverage our synergistic portfolio in oncogenic pathways, immuno-oncology, and DNA Damage Response (DDR) to tackle challenging tumor types in gastrointestinal, genitourinary, and head and neck and thoracic cancers. Learn more at https://www.merckgrouponcology.com .
All Merck Press Releases are distributed by e-mail at the same time they become available on the Merck Website. Please go to www.merckgroup.com/subscribe to register online, change your selection or discontinue this service.
About Merck
Merck, a leading science and technology company, operates across healthcare, life science and electronics. Around 58,000 employees work to make a positive difference to millions of people’s lives every day by creating more joyful and sustainable ways to live. From advancing gene editing technologies and discovering unique ways to treat the most challenging diseases to enabling the intelligence of devices – the company is everywhere. In 2020, Merck generated sales of € 17.5 billion in 66 countries.
Scientific exploration and responsible entrepreneurship have been key to Merck’s technological and scientific advances. This is how Merck has thrived since its founding in 1668. The founding family remains the majority owner of the publicly listed company. Merck holds the global rights to the Merck name and brand. The only exceptions are the United States and Canada, where the business sectors of Merck operate as EMD Serono in healthcare, MilliporeSigma in life science, and EMD Electronics.
View source version on businesswire.com: https://www.businesswire.com/news/home/20210930005596/en/
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Heath Hoglund Joins Sisvel as Chief IP Officer7.1.2026 07:00:00 CET | Press release
Sisvel is pleased to announce the appointment of Heath Hoglund as the company’s first-ever Chief Intellectual Property Officer. In this role he will be fully responsible for the firm’s patent pools on a global basis. One of the world’s top IP dealmakers, Hoglund joins Sisvel having taken the decision to leave Via Licensing, where he was an outstanding President for four years. Prior to that, he had been Vice-President of IP and Standards at Dolby, overseeing the company’s patent portfolio, its patent licensing programmes, and leading on the formation and design of numerous patent pools and standards initiatives. The appointment creates a new Licensing and Programme Management leadership structure at Sisvel. This will strengthen collaboration between the functions, increasing Sisvel’s considerable growth potential. Licensing and Programme Management heads, Nick Webb and David Muus, will continue to lead their respective areas, retaining all current responsibilities. Heath Hoglund’s trac
SymphonyAI and Matas Group are Redefining Health & Beauty in the Nordics With AI7.1.2026 06:07:00 CET | Press release
Matas Group partners with SymphonyAI to streamline category management, elevate the customer experience, and accelerate growth across key Nordic markets In the ever-evolving health and beauty landscape, Matas Group continues to set the standard for innovation and customer care. As the largest retailer in its sector across Denmark, Sweden, Finland, and Norway, Matas Group is committed to delivering unified, data-driven experiences to millions of customers — both online and in-store. That commitment now takes a leap forward as Matas selects SymphonyAI, a global leader in Vertical AI platforms, as its partner to modernize category management across the entire enterprise. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260107270530/en/ Exterior of a Matas Group retail store in Scandinavia. The leading Nordic health and beauty retailer is expanding its category management capabilities through a new partnership with SymphonyAI. Fol
Lenovo Supercharges Enterprise AI with the Launch of Agentic AI and Lenovo xIQ to Deliver Full-Lifecycle Hybrid AI at Scale7.1.2026 02:00:00 CET | Press release
Lenovo Agentic AI gives organizations the governance, tools, advice, and ongoing support needed to deploy and manage production-ready AI agents faster and smarter – turning AI ambition into measurable impact.Three new Lenovo xIQ delivery platforms strengthen Lenovo’s Hybrid AI Advantage™ by delivering the automation and governance enterprises need to scale AI with confidence. Lenovo today announced the next phase of its Hybrid AI Advantage™ with the launch of Lenovo Agentic AI, a new full-lifecycle enterprise solution for creating, deploying, and managing AI agents, and Lenovo xIQ a new suite of AI-native delivery platforms designed to simplify, accelerate, and operationalize AI across the enterprise. This evolution extends Lenovo’s established Hybrid AI Advantage™ from a foundational AI architecture to a more complete, lifecycle-driven approach for deploying and scaling AI across the enterprise. Lenovo Hybrid AI Advantage™ is Lenovo’s end-to-end enterprise AI portfolio, providing the
Lenovo Defines the Next Era of Hybrid AI with Personalized, Perceptive, and Proactive AI Portfolio at Tech World @ CES 20267.1.2026 02:00:00 CET | Press release
Lenovo announces Lenovo and Motorola Qira personal agentic AI across devices, new Motorola flagship smartphones, expanded portfolio of AI PCs, visionary proofs of concept including agentic-native wearables, and revolutionary inferencing servers alongside breakthroughs in AI technologies for FIFA, Formula 1®, and entertainment. Today at Tech World @ CES 2026 at Sphere in Las Vegas, Lenovo unveiled the boldest innovations yet for the future of Hybrid AI, introducing a new personal AI super agent, AI PCs and smartphones, proofs of concept including agentic-native wearables, next-generation enterprise AI infrastructure, and breakthrough industry collaborations in entertainment and sports. Building on years of AI innovation across devices, infrastructure, solutions, and services, Lenovo demonstrated how AI is now personal, perceptive, proactive, and everywhere. Lenovo’s new offerings adapt to individuals and organizations, operating as digital twins to orchestrate actions across ecosystems
Lenovo Teams with NVIDIA on Gigawatt AI Factories Program to Accelerate Enterprise AI7.1.2026 02:00:00 CET | Press release
High-velocity solutions enable AI cloud providers to achieve faster time-to-first token, accelerating ROI and production-ready AI servicesPartner acceleration program combines solutions, services and manufacturing to deliver AI at giga-scale, enabling seamless scaling to millions of GPUs for next-generation workloads Today at Tech World @ CES 2026 at Sphere in Las Vegas, Lenovo (HKSE: 992) (ADR: LNVGY) unveiled the Lenovo AI Cloud Gigafactory with NVIDIA, expandingand reinforcing its partnership with NVIDIA through a shared commitment to accelerating hybrid AI adoption across personal, enterprise and public AI platforms. During his keynote,Lenovo Chairman and CEO Yuanqing Yang, joined by NVIDIA founder and CEO Jensen Huang, debuted this new gigawatt-scale AI factory program as a major advancement that enables AI cloud providers to bring next generation AI workloads and applications online faster, moving customers from creation to production at unprecedented scale. “In the AI era, value
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom