HEARTSEED
11.6.2021 09:02:11 CEST | Business Wire | Press release
Heartseed , a Tokyo-based biotechnology company developing iPSC-derived cardiomyocytes for heart failure (HF), today announced it has raised 4 Billion-yen (approx. $37 Million) at Series C round, bringing its total financial backing to 8.2 Billion yen (approx. $75 Million) since its foundation in 2015.
New investors are UTokyo Innovation Platform Co. (UTokyo IPC), Medical Incubator Japan, Keio Innovation Initiative (KII), and Sumitomo Mitsui Trust Investment. Among the existing investors, SBI Group, Nissay Capital, SMBC Capital, Medipal Holdings, and Itochu Chemical Frontier participated in this round.
Heartseed will use the new funds to accelerate the initiation of global clinical trial of HS-001 for HF as well as to confirm its proof of concept in Phase 1/2 LAPiS study in Japan. Additionally, Heartseed will also examine a less invasive administration such as transendocardial injection using a catheter.
“Heartseed has made a strong progress in our research and development of our cardiac remuscularization therapy, as proved by the clearance of clinical trial application of Phase I/II LAPiS Study by the Japanese Pharmaceutical and Medical Agency and many awards we received.” said Professor. Keiichi Fukuda, co-founder and CEO at Heartseed. “The commitment from both new and existing investors in this round is a strong validation of our technology and strategic vision. With their support, we look forward to accelerating our development to deliver potentially curative therapy for heart failure across the globe.”
About HS-001
Heartseed's lead pipeline, HS-001, is allogeneic iPSC-derived, highly purified ventricular cardiomyocyte spheroids. By forming micro-tissue-like spheroids, retention rate and viability of cell transplant are improved. The spheroids are transplanted using a special administration needle (SEEDPLANTER®) and guide adapter developed for safe and efficient administration of the spheroids into the myocardial layer of the heart.
The expected mechanism of action is that the transplanted cardiomyocytes electrically couple with the patient's myocardium to improve cardiac output by remuscularization, and secretion of angiogenic factors to form new blood vessels around the transplant site (neovascularization).
The review of the Clinical Trial Application of a phase I/II clinical trial (LAPiS Study) evaluating the safety and efficacy of HS-001 for the treatment of heart failure caused by ischemic heart disease in Japan was successfully completed in March 2021 by Japan's Pharmaceutical and Medical Devices Agency.
For details: http://www.heartseed.jp/en/index.html
View source version on businesswire.com: https://www.businesswire.com/news/home/20210611005010/en/
Link:
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Phison's Pascari Enterprise Storage Honored with COMPUTEX Best Choice Golden Award for Breakthrough 245.76 TB Capacity21.5.2026 08:30:00 CEST | Press release
Latest PCIe Gen5 SSD lowers costs at scale for optimized data center OPEX Phison Electronics (8299TT), a global leader in NAND flash controllers and storage solutions, today announced that its Pascari D206V PCIe Gen5 data center SSD has received the prestigious COMPUTEX Best Choice Golden Award, recognizing the next generation of innovation in ultra-high-capacity enterprise storage for AI and modern data center infrastructure. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260520865786/en/ Pascari D206V Wins COMPUTEX Best Choice Golden Award in 2026 The Pascari D206V is designed to address the growing industry challenge of efficiently scaling storage capacity for AI, cloud and data-intensive workloads without increasing operational complexity or infrastructure costs. Delivering up to 245.76 TB in a single U.2 PCIe Gen5 SSD, the D206V enables hyperscale and enterprise customers to significantly increase storage density while
Truecaller Travel eSIM Launch Powered by Telness Tech’s Seamless OS21.5.2026 08:30:00 CEST | Press release
Telness Tech, the telecom software company behind Seamless OS, today announced that Truecaller’s newly launched Travel eSIM service is powered by its platform. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260520906699/en/ Telness Tech, the telecom software company behind Seamless OS, today announced that Truecaller’s newly launched Travel eSIM service is powered by its platform. Truecaller, the leading global platform for verifying contacts and blocking unwanted communication, has launched Travel eSIM across 29 countries, marking the company’s move into mobile data services. The launch broadens Truecaller’s platform beyond caller ID and spam protection, and for the first time adds digital consumables to the portfolio. With more than 500 million people already using Truecaller in their daily communication, Travel eSIM extends that relationship to international travel — a category where users routinely overpay for connectivi
AHS Properties: At 26, Abbas Sajwani Is Deploying Billions Into Dubai’s Future21.5.2026 08:00:00 CEST | Press release
Named the youngest billionaire in real estate globally by Forbes, the AHS Properties founder is scaling a AED 50 billion pipeline on a single conviction: Dubai is no longer a luxury market - it’s a capital destination. While global real estate capital recalibrates, Abbas Sajwani is accelerating. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260519804834/en/ Abbas Sajwani, Founder and CEO of AHS Properties. (Photo: AETOSWire) The 26-year-old Founder and CEO of AHS Properties - recently recognised by Forbes as the youngest Arab billionaire and the youngest billionaire globally in real estate, with a net worth of $1.9 billion - is building one of the fastest-scaling development platforms in Dubai. Since launching in 2021, AHS Properties has expanded from ultra-luxury villa redevelopments into a multi-billion-dollar portfolio spanning waterfront residential, Grade-A commercial, and large-scale mixed-use developments across Duba
Xsolla and the Dubai Films and Games Commission Create a Strategic Partnership to Connect Dubai-Based Developers to Global Markets21.5.2026 05:16:00 CEST | Press release
Multi-Year Agreement Creates Opportunities to Build All The Things for Video Games in Dubai and MENA Xsolla, a leading global video game commerce company, and the Dubai Games Commissioner, in coordination with the Dubai Films and Games Commission, announced a multi-year strategic partnership to accelerate the development of the video game industry and expand commercial access for developers operating across the Middle East and North Africa. The announcement was made at GamesBeat Summit 2026 in Los Angeles, California. The partnership will unite Xsolla's global commerce infrastructure, including direct-to-consumer storefronts, intelligent payments across 1,000+ payment methods in 200+ geographies, and player engagement tools, with DFGC's mandate to establish Dubai as a world-class destination for video game development and publishing. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260520329315/en/ Xsolla and the DFGC partner
Marquee Brands Enters Strategic Partnership With DAMAC Group for a Majority Interest in Roberto Cavalli20.5.2026 20:30:00 CEST | Press release
The Partnership Positions Roberto Cavalli for a New Phase of Global Expansion and Omnichannel Growth Marquee Brands, the premier global brand management company and leading brand accelerator, today announced a definitive agreement for a majority interest in Roberto Cavalli, through a strategic partnership with DAMAC Group, the leading Dubai-based global conglomerate and luxury real estate developer. The transaction is expected to close in the second quarter of 2026, after which DAMAC Group will remain a significant shareholder. Founded in Florence in 1970, Roberto Cavalli the iconic luxury house celebrated for its avant-garde design and distinct Italian craftsmanship joins Marquee Brands’ portfolio of timeless global brands, including Martha Stewart, Laura Ashley, Sur La Table, BCBGMAXAZRIA and Stance. The addition of Roberto Cavalli further strengthens Marquee Brands’ position as a leader in the luxury and lifestyle sectors, bringing total portfolio-wide retail sales to approximately
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom