Business Wire

GALDERMA

Share
Alluzience®, the first ready-to-use BoNT-A neuromodulator, receives positive decision for use in Europe

Galderma today announced that Alluzience® has completed its European decentralized procedure resulting in a positive decision for the first ready-to-use neuromodulator, a wrinkle relaxing injection, in Europe. National approvals will now take place across the region in line with local processes in each country. Designed for precision, Alluzience® is a liquid form of botulinum toxin type A intended for use in adult patients as a treatment to temporarily improve the appearance of moderate to severe glabellar lines (vertical lines between the eyebrows), when the severity of these lines has an important psychological impact on the patient.1

"The introduction of Alluzience® marks a new era in treatment innovation for upper facial lines in Europe. Like many aspects of physical appearance, glabellar lines can have a significant impact on patients’ confidence and wellbeing. I’ve heard first-hand that the transition to living and working in a virtual world has only exacerbated these issues.

As the first ready-to-use neurotoxin in Europe, Alluzience® is fit for the needs of today; it will allow me to consistently optimize results and deliver patient satisfaction with more precision. Most importantly, it will help people to feel confident in themselves again.”
Dr Joanna Czuwara, MD, PhD, Associate Professor, Department of Dermatology, Warsaw Medical University, Poland

As people age, the skin and underlying muscles play a significant role in the emergence of noticeable lines and folds, including glabellar lines between the eyebrows.2 Clostridium botulinum toxin type A (BoNT-A), the active ingredient in Alluzience® , is often used to smooth facial lines including glabellar lines.2 All currently approved BoNT-A products (or formulations) in Europe come in powder form and require reconstitution with sodium chloride before use.2 The ready-to-use liquid formulation of Alluzience® avoids any calculations and allows for more precision, meaning it has the potential to improve safety and dosing accuracy compared with powder form BoNT-A preparations.2 Alluzience® was developed using novel production technologies meaning it is free from human and animal-derived proteins such as human serum albumin and lactose.1

The European Marketing Authorization Application of Alluzience® is based on pooled data from two pivotal trials of 372 patients with moderate to severe glabellar lines who were treated with either Alluzience® (n=250) or placebo (n=122). These data demonstrated that >50% of patients reported an effect within two to three days, including 23% of patients within one day.1 An effect was demonstrated for up to six months after injection with Alluzience® .1 The responder rate at day 29 was significantly higher for patients treated with Alluzience® compared to placebo (primary endpoint) (p<0.0001).1

Additionally, patients’ level of satisfaction one month following injection showed that 85.2% of the patients receiving Alluzience® were either satisfied or very satisfied compared to 9% for placebo patients.1 The majority of adverse reactions reported with Alluzience® in clinical trials were of mild to moderate intensity and reversible.1 The most frequently reported adverse reactions were headache and injection site reactions.1

"At Galderma we pride ourselves on developing innovative products that meet today’s needs, which is underpinned by our longstanding knowledge and heritage in dermatology. We know how advantageous it is for doctors to have access to a ready-to-use liquid formulation in Alluzience® . It’s for this reason that today's news is an important milestone for both patients and healthcare professionals.”
Alexandre Brennan - Head, Global Business Unit for Aesthetics

About Galderma

Galderma is the world’s largest independent dermatology company, present in approximately 100 countries. Since our inception in 1981, we have been driven by a complete dedication to dermatology. We deliver an innovative, science-based portfolio of sophisticated brands and services across Aesthetics, Consumer Care and Prescription Medicine. Focused on the needs of consumers and patients, we work in partnership with healthcare professionals to ensure superior outcomes. Because we understand that the skin we’re in shapes our life stories, we are advancing dermatology for every skin story.

For more information: www.galderma.com.

About Alluzience® (liquid botulinum toxin type A)

Alluzience® (liquid botulinum toxin type A) is the first ready-to-use BoNT-A liquid neuromodulator formulation to be introduced in Europe. Alluzience® should only be administered by a physician with appropriate qualifications and expertise in this treatment using the required equipment.1 Dosing and treatment intervals depend on assessment of the individual patient’s response.1 The treatment interval should be no more frequent than every three months.1 For more information, please see the Summary of Product Characteristics.1

Alluzience® is a product under license from Ipsen. Alluzience® is a registered trademark of Ipsen. Galderma has an exclusive license from Ipsen to develop, promote and distribute Alluzience® in the approved indication in Europe (excluding Czech Republic, Slovakia, Greece, Lithuania, Estonia, Latvia, Hungary).


1 Alluzience Summary of Product Characteristics.
2 Ascher B, Rzany B, Kestemont P, et al. Liquid Formulation of AbobotulinumtoxinA: A 6-Month, Phase 3, Double-Blind, Randomized, Placebo Controlled Study of a Single Treatment, Ready-to Use Toxin for Moderate-to-Severe Glabellar Lines. Aesthet Surg J . 2020;40(1):93–104.

Job code: GL-ALZ-2100026
Date of preparation: June 2021

About Business Wire

Business Wire
Business Wire
101 California Street, 20th Floor
CA 94111 San Francisco

http://businesswire.com

Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

SES Receives All Required Regulatory Approvals to Complete Intelsat Acquisition14.7.2025 22:15:00 CEST | Press release

SES received the final regulatory approvals for the SES-Intelsat transaction, including the US Federal Communications Commission. On 30 April 2024, SES and Intelsat announced an agreement for SES to acquire Intelsat for a cash consideration of $3.1 billion (€2.8 billion). The transaction was subject to receipt of relevant regulatory clearances and other relevant requirements which all have now been obtained. As a result, SES plans to close the transaction on or about Thursday, 17 July 2025. Once closing has occurred, a press release will be published to confirm that the transaction has successfully closed. Follow us on: Twitter | Facebook | YouTube | LinkedIn | Instagram Read our Blogs > Visit the Media Gallery > About SES SES has a bold vision to deliver amazing experiences everywhere on Earth by distributing the highest quality video content and providing seamless data connectivity services around the world. As a provider of global content and connectivity solutions, SES owns and ope

Loomis Sayles Celebrates 15 Years of Growth Equity Strategies Team Under Leadership of Aziz V. Hamzaogullari14.7.2025 22:05:00 CEST | Press release

Loomis, Sayles & Company: This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250714614048/en/ 90.7 160 1 BILLION IN ASSETS UNDER MANAGEMENT COMBINED YEARS OF INVESTMENT EXPERIENCE INVESTMENT PHILOSOPHY GES Team As of 5/31/2025 GES Team As of 5/31/2025 Supported by a seven-step research framework Loomis, Sayles & Company proudly celebrates the 15-year anniversary of a differentiated approach to growth equity investing under the leadership of Aziz V. Hamzaogullari, CFA, the founder, chief investment officer and portfolio manager of the Loomis Sayles Growth Equity Strategies (GES) Team. Aziz is also an executive vice president and a member of the firm’s Board of Directors. GES is a cohesive team with nearly 19 years of alpha generation and a long-term, private equity approach to investing. Under Aziz Hamzaogullari’s leadership since 2010, assets under management for GES have grown from $1.9 billion to nearly $91 billion as of 31 Ma

Cessna Skyhawk Soars With Enhanced Efficiency: Solid-State Dual Electronic Ignition System Introduced to the Industry-leading Piston14.7.2025 18:00:00 CEST | Press release

The industry-leading training aircraft, the Cessna Skyhawk, now features a dual electronic ignition system (dual EIS), enhancing maintenance, efficiency and overall operation of the single-engine, high-wing piston. The dual Lycoming electronic ignition system is now standard on all new Cessna Skyhawk aircraft. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250714759359/en/ Cessna Skyhawk soars with enhanced efficiency: solid-state dual electronic ignition system introduced to the industry-leading piston (Photo Credit: Textron Aviation) The Cessna Skyhawk is designed and produced by Textron Aviation Inc., a Textron Inc. (NYSE: TXT) company. The dual EIS replaces the previous dual magneto ignition system on the Skyhawk, incorporating advanced electronic components and reducing the number of internal moving parts to optimize operation. This solid-state electronic technology improves maintenance intervals, fuel efficiency and en

The 2025 Empire State Building Run-Up Returns Oct. 814.7.2025 17:48:00 CEST | Press release

Presented by NYU Langone Health and Powered by the Challenged Athletes FoundationLottery Opens July 14 The Empire State Building (ESB) announced today general lottery registration for the annual Empire State Building Run-Up (ESBRU) on Oct. 8, 2025, at 8 p.m. ESB also announced the ESBRU will be presented by NYU Langone Health and powered by the Challenged Athlete’s Foundation. General lottery registration will be open from July 14 through July 28, 2025. In the 47th annual Run-Up, 225 runners will race up the iconic building’s 1,576 stairs to the world-famous Observatory. This year’s heats will include elite men and women, media, celebrities, New York City real estate brokers, building tenants, CAF athletes, members of the NYPD and FDNY, and the public, among others. On July 30, registered runners will be notified of their race status with participation costs of $175 per runner to be charged only upon acceptance from the lottery. “We are delighted to welcome NYU Langone Health as our ne

Taicang: A Model for China-Europe ESG Cooperation14.7.2025 16:11:00 CEST | Press release

Located in the Yangtze River Delta, Taicang City in Jiangsu Province is known as the “Hometown of German Enterprises in China.” At the recent 2nd Sino-European Corporate ESG Best Practice Conference, Taicang received the prestigious “Zero-Carbon City” Best Practice Award, further solidifying its reputation as a benchmark for green urban transformation. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250714458209/en/ A glimpse of Taicang City, Jiangsu Province, China. According to the jury, “By integrating ESG indicators into its urban development strategy, Taicang has demonstrated visionary leadership and has become a model for sustainable city and industrial development.” In response to the global challenges of climate change and sustainable growth, Taicang has proactively aligned with China’s “dual carbon” strategy. It has positioned itself as a modern garden city driven by green development, integrating ESG principles into

In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.

Visit our pressroom
World GlobeA line styled icon from Orion Icon Library.HiddenA line styled icon from Orion Icon Library.Eye