CA-CROWN-BIOSCIENCE
7.1.2021 19:18:22 CET | Business Wire | Press release
Crown Bioscience, a JSR Life Sciences company, today announced the expansion of their state-of-the-art NGS capabilities, together with the launch of proprietary NGS panel services , providing increased opportunities for pharmaceutical partners to better understand drug mechanisms of action (MOA) and to develop predictive biomarkers for their investigational drug candidates.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20210107005802/en/
The newly built, comprehensive suite of NGS capabilities provides clients with a streamlined multi-omics workflow of high-quality services, enabling full genomic understanding, including global gene expression, mutations, and genomic structures. This is a significant addition to CrownBio’s current preclinical and translational services, allowing clients greater insight into disease mechanisms, drug MOAs, and responder patient populations, to ultimately accelerate successful development of effective therapies.
The expanded services have been established at the Company’s Center of Translational Science in Suzhou, China, to meet increased client demand for whole genome sequencing (WGS), including Illumina’s Novaseq 6000 and BGI’s MGISEQ-2000 second generation sequencing platform. PacBio’s third generation Sequel Ⅱ sequencing platform allows for high throughput, high accuracy long-read NGS, and Bionano’s Saphyr® Genome Imaging enables large structural variant analysis and genome mapping. Comprehensive data analysis pipelines have also been built, together offering highly sensitive genome assembly and discovery algorithms.
“With our range of validated services, we can help drug developers improve the accuracy, sensitivity and speed at which they progress their new agent programs via discovery of MOAs and predictive biomarkers,” said Henry Li, PhD, chief scientific officer at CrownBio. “This type of multi-omics data is essential to understand the clinical populations that respond to anticancer agents and progress cancer treatments.”
In addition to the validated commercial platforms, CrownBio has also developed various powerful biomedical applications using NGS platforms, including NGS panels for bio-sample authentication, contamination detection and quantification, mouse tumor microenvironment profiling and metagenomic sequencing services for microbiome analysis. Custom NGS services are also available for clients who wish to utilize CrownBio’s expertise and large model biobank.
“Quality downstream applications are key to maximizing the full potential of in vivo study results, including our wealth of historical model and treatment data,” said Sheng Guo, PhD, head of bioinformatics at CrownBio. “These are leveraged by a highly experienced team and a proprietary, published algorithm to provide important biomarker discovery and drug mechanism probing services.”
These NGS services are available for client use immediately including our newly launched mouse I/O profiling targeted RNA-seq panel . The panel will allow deep profiling of the immunogenomics of murine tumor-immune interactions through the measurement of 1080 transcripts from a single sample.
About Crown Bioscience Inc.
Crown Bioscience, a JSR Life Sciences company, is a global drug discovery and development service company providing translational platforms to advance oncology, inflammation, and metabolic disease research. With an extensive portfolio of relevant models and predictive tools, Crown Bioscience enables clients to deliver superior clinical candidates. For more information, visit:
● https://www.jsrlifesciences.com
View source version on businesswire.com: https://www.businesswire.com/news/home/20210107005802/en/
Link:
Social Media:
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Torq Acquires Jit to Unleash the First Enterprise AI SOC Context Graph—and Rewrite the Future of SecOps19.5.2026 15:00:00 CEST | Press release
With Jit Acquisition, Torq Catapults Enterprise SOCs Into a New Realm of Detailed Contextual Investigations That Drive Precision Decision-Making Torq, the established agentic security operations leader, today announced the acquisition of Jit, the Boston-based AI Context Graph cybersecurity pioneer. This move marks a dramatic leap forward for the Torq AI SOC Platform by ensuring agentic investigations are precisely informed via organization-specific contextual data. This shift redefines agentic reasoning, moving beyond static facts such as users, devices and their relationships, to prioritize live, dynamic contextual data overlaid on top, including business drivers, and the real-time state of the enterprise. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260519044833/en/ Instead of acting on fragmented data or having investigations triggered by a single alert, Torq AI operates with a unified, continuously-updated, contextual
Nine in 10 Firms Fear In-House Systems Can’t Keep Pace with Executive Pay Demands19.5.2026 15:00:00 CEST | Press release
89% of senior HR, rewards, and compensation leaders say in-house technology cannot keep pace with executive compensation demands80% report increased participation in incentive schemes over the past three years66% identify reliance on multiple service providers as a key barrier to maintaining accurate and consistent data Managing executive compensation is a growing challenge for financial services firms, with nearly nine in 10 (89%) saying their in-house technology can’t keep pace with demand. New research by CSC, the leading provider of business administration and compliance solutions, shows that rising complexity, regulatory pressure, and expanding global participation place increasing strain on internal systems and teams.1 CSC surveyed 300 senior HR, rewards, and compensation leaders across Europe, Asia Pacific, and North America working in private markets, asset management, insurance, and investment banking. The report, The Future of Reward in Financial Services: Executive Compensat
Tacton Appoints Manufacturing Technology Leader Mike DiTullio to Board of Directors19.5.2026 15:00:00 CEST | Press release
Former PTC President & COO brings decades of experience serving complex manufacturers and scaling global commercial organizations as Tacton advances growth in North America and EMEA. Tacton, a global leader in Configure, Price, Quote (CPQ) solutions for manufacturers of complex products, today announced the appointment of Mike DiTullio to its Board of Directors. DiTullio is an enterprise software executive with more than three decades of experience working with complex manufacturers. He joins at a pivotal moment in the company’s evolution as Tacton expands beyond CPQ to deliver the Buyer-Centric Smart Factory, a connected approach that unites buyer engagement, engineering, and order fulfillment into a single intelligent system. DiTullio spent 26 years at PTC, most recently as President and Chief Operating Officer, wherehe worked closely with leading manufacturers to transform how they design, sell, and deliver complex products. In that role, he led global commercial operations across s
Echodyne and Moog SuccessfullyDemonstrate Reconfigurable Integrated-weapon Platform (RIwP®) at U.S. Army Exercise19.5.2026 15:00:00 CEST | Press release
Demonstration showed how combining advanced radar, sophisticated control systems, and AI can turn existing kinetic weapons into highly effective C-UAS effectors Echodyne, the radar platform company, and Moog Inc. (NYSE: MOG.A and MOG.B), a worldwide designer, manufacturer, and systems integrator of high performance precision motion and control systems, announce the results of testing of their defensive systems to counter small offensive UAS (“sUAS”) weapons. Capabilities Tested Live detection, lock on with precision tracking, and successfully engaging of Group 1-3 UAS threats in less than 3 seconds. Combined AI targeting, wireless fire control, and radar integration across mission equipment capabilities for defense against small UAS weapons. AI targeting for passive detection, autonomous targeting, track re-acquire, multi-object targeting. Outputs Identified and swiftly rectified critical capability gaps within a simulated battlefield environment. Proved that combining precision data w
NordicTrack’s Most Ambitious Pilates Machine Yet: Introducing the Ultra 1 Reformer19.5.2026 15:00:00 CEST | Press release
NordicTrack is bringing studio-grade Pilates directly into the home with the Ultra 1 Reformer, available to order May 19 at NordicTrack.com for $US4,999. Blending luxury craftsmanship with smart technology, this consumer-focused model offers a studio‐quality Pilates experience that fits effortlessly into modern living. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260519139005/en/ NordicTrack Ultra 1 Reformer Pilates has become a cornerstone of modern wellness, recognized for building core strength, improving flexibility, and fostering a deep mind-body connection. Recognizing this growing demand, NordicTrack’s new reformer pairs elegant design with an integrated HD touchscreen and seamless access to expert‐led classes through the iFIT platform. “The Ultra 1 Reformer is the first Pilates machine that earns its place in your home. Real equipment, personalized expert instruction, and the results we are all seeking,” says Kevin
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom