BOEHRINGER-INGELHEIM
In the first half of 2021, Boehringer Ingelheim has supplied more humans and animals worldwide with innovative medicines than ever before. The company’s success is based on its rich R&D portfolio with a focus on diseases with high unmet medical need. The R&D pipeline in Human Pharma comprises more than 60 new substances and around 100 clinical and pre-clinical projects. This pipeline has the potential to deliver up to 15 medicines for approval by 2025.
In July, Boehringer Ingelheim reported a breakthrough in the treatment of heart failure with empagliflozin (marketed as JARDIANCE® ). More than 60 million patients worldwide suffer from this disease, approx. half of them from heart failure with preserved ejection fraction (HFpEF). Heart failure with left ventricular preserved ejection fraction occurs when the left ventricle of the heart is unable to fill properly, resulting in less blood being pumped to the body. A recent trial showed a significantly lower risk with empagliflozin of hospitalization for heart failure or cardiovascular death in adult patients with HFpEF. If approved, empagliflozin from Boehringer Ingelheim would become the first and only clinically proven therapy to improve outcomes across the full spectrum of heart failure patients regardless of ejection fraction. In June, the European Commission granted marketing authorization for JARDIANCE® as a treatment for adults with symptomatic chronic heart failure with reduced ejection fraction (HFrEF).
“Despite all the medical progress made in recent decades, there are still many diseases for which there is yet no adequate treatment available. That is why we at Boehringer Ingelheim focus on areas where the need for medical innovation is high,” said Hubertus von Baumbach, Chairman of the Board of Managing Directors. “Our strong R&D pipeline has made further, decisive progress in the first half of 2021. These medical successes have the potential to improve the lives of millions of patients worldwide.”
Progress in mental health pipeline
Boehringer Ingelheim also made progress in the area of neuropsychiatric disorders, including two ongoing phase II trials. At the end of May, Boehringer Ingelheim announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for BI 425809, a key component of the company’s mental health research program, for the treatment of Cognitive Impairment Associated with Schizophrenia (CIAS). Boehringer Ingelheim also announced the planned initiation of the innovative CONNEX Phase III clinical trial program assessing the safety and efficacy of BI 425809, a novel glycine transporter-1 (GlyT1) inhibitor, for improving cognition in adults with schizophrenia.
The company supplemented its own research and development capabilities and medical pipeline with further high-profile partnerships, among others in the fields of quantum computing and data science. In June, Boehringer Ingelheim became a founding member of the Quantum Technology and Application Consortium (QUTAC), which unites ten of the leading German companies in exploring industrial applications for quantum computing. Quantum computing holds enormous potential for pharmaceutical research and development, particularly for early research processes in which Boehringer Ingelheim has a high level of expertise.
Boehringer Ingelheim also remains committed to the search for potential therapeutics against the SARS-CoV-2 virus. In July, the company announced that it will focus its COVID-19 therapy research on the development of alteplase as a potential treatment for COVID-19 patients with severe breathing problems, called acute respiratory distress syndrome (ARDS). The decision is based on favorable safety and efficacy data from an interim analysis of the TRISTARDS Phase 2/3 study, following completion of the Phase 2b part of the study including 62 patients. The BI 767551 SARS-CoV-2 neutralizing antibody development program will be discontinued, as the current state of the pandemic makes it challenging to further progress clinical development of this antibody and make it available to patients within a reasonable time frame to contribute against the COVID-19 pandemic.
Solid business performance despite ongoing pandemic effects
Following a successful financial year 2020, Boehringer Ingelheim continued its positive trend in the first half of 2021. In the first six months, the company generated net sales of 9.8 billion EUR, up 5.8 percent (year on year and adjusted for currency effects). All three business areas (Human Pharma, Animal Health, Biopharmaceutical Contract Manufacturing) contributed to the net sales growth.
“Together with our employees, we achieved solid financial results in the first half of the year, even when the COVID-19 pandemic continues to have an impact,” said Michael Schmelmer, member of the Board of Managing Directors with responsibility for Finance & Group Functions. “We see that in a lot of countries, people avoid seeing their doctors because of COVID-19, even if they are in urgent need of diagnosis and treatment. This non-treatment poses a serious medical problem, which we must take into consideration even more when fighting the pandemic.”
Human Pharma: JARDIANCE® and OFEV® growth drivers
In Human Pharma, Boehringer Ingelheim achieved net sales of 7.1 billion EUR in the first half of the year, equal to the high level of last year. Adjusted for currency effects, net sales increased by 5 percent year on year.
Growth in Human Pharma continues to be driven by the SGLT-2 inhibitor JARDIANCE® and the respiratory medicine OFEV® . Net sales generated by JARDIANCE® increased by 17.2 percent (year on year and adjusted for currency effects) to 1.4 billion EUR. Boehringer Ingelheim has co-developed and markets JARDIANCE® together with Eli Lilly and Company. Net sales of the respiratory product OFEV® increased by 28.9 percent (year on year and adjusted for currency effects) and amounted to 1.2 billion EUR. OFEV® is approved for the treatment of people living with idiopathic pulmonary fibrosis (IPF) in more than 80 countries, for systemic sclerosis-associated ILD (SSc-ILD) in more than 70 countries, and for other chronic fibrosing interstitial lung diseases with a progressive phenotype (PF-ILDs) in more than 60 countries.
Animal Health shows good results in pet and livestock business
Boehringer Ingelheim has a full pipeline of R&D projects to develop innovative solutions for the health of pets and livestock. One example is the clinical trial on velagliflozin, a SGLT2-inhibitor with therapeutic potential to treat diabetes in cats. Velagliflozin has been developed primarily for use in treating Type 2 diabetes in humans by lowering blood sugar and now provides an opportunity for application in animal health. To complement its own R&D portfolio, Boehringer Ingelheim has entered into promising new partnerships in the area of animal health. In the first half of 2021 this included partnerships with PetMedix for the development of new and transformative antibody therapeutics for pets, and with Lifebit Biotech to detect and early-report global infectious disease outbreaks by using Artificial Intelligence.
In the first half of 2021, Boehringer Ingelheim generated strong net sales of around 2.3 billion EUR in the Animal Health business area. Adjusted for currency effects, year-on-year sales were up 9.6 percent in this highly competitive market.
The antiparasitic medicine NEXGARD® for dogs remained the best-selling product with net sales up 16.4 percent (year on year and adjusted for currency effects) to 488 million EUR. FRONTLINE® , which is indicated for the treatment and prevention of fleas, ticks and chewing lice in dogs and cats, generated net sales of 267 million EUR, up 8.9 percent (year on year and adjusted for currency effects).
Net sales of HEARTGARD® , the heartworm prevention product for dogs, declined slightly by 0.2 percent (year on year and adjusted for currency effects) to 173 million EUR. Net sales of the swine vaccine INGELVAC CIRCOFLEX® continued to recover in many countries with the decline of African swine fever. INGELVAC CIRCOFLEX® sales grew by 18.1 percent (year on year and adjusted for currency effects) to 145 million EUR.
Biopharmaceutical Contract Manufacturing: Inauguration of new production facility in Vienna, Austria, in October
Demand in Biopharmaceutical Contract Manufacturing remains high. Net sales rose 1.1 percent (year on year and adjusted for currency effects) to 322 million EUR. Boehringer Ingelheim is further expanding its biopharmaceutical production capacity to continue to meet growing demand. The company will inaugurate its large-scale cell culture (LSCC) facility in Vienna, Austria, in October, including up to 150,000L manufacturing capacities for Boehringer Ingelheim products and contract manufacturing.
Please click on the following link for ‘Notes to Editors’:
http://www.boehringer-ingelheim.com/press-release/boehringer-ingelheims-half-year-figures-2021
View source version on businesswire.com: https://www.businesswire.com/news/home/20210803005445/en/
Link:
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Elegen and Nutcracker Therapeutics to Pilot First Fully Cell-Free Manufacturing Process for RNA-based Personalized Cancer Therapeutics11.7.2025 14:00:00 CEST | Press release
Fully cell-free process aims to further democratize personalized cancer therapeutic manufacturing with shorter turnaround times and negligible bioburden and endotoxin risks. Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, today announced the launch of a pilot program to demonstrate the industry’s first fully synthetic, cell-free manufacturing platform for RNA-based personalized cancer therapeutics (PCTs). The pilot marks another step toward making PCTs more accessible, timely, and scalable. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250711152688/en/ As late-stage PCT clinical trials progress and therapy developers work to create the next generation of PCTs, the speed, reliability, scaling and cost of traditional production methods pose a major challenge. Specifically, the first step of DNA template production is hi
$MBG Token Pre-Sale Set for July 15 — Only 7 Million Tokens Available at $0.3511.7.2025 10:17:00 CEST | Press release
MultiBank Group, the world’s largest financial derivatives institution headquartered in Dubai, has confirmed that its highly anticipated $MBG Token pre-sale will go live on July 15, with demand expected to be intense. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250711737311/en/ With only 7 million $MBG tokens up for grabs at an exclusive entry price of $0.35, this is a rare opportunity to secure early access to what many are calling the year’s most powerful utility asset. With only 7 million tokens up for grabs at an exclusive entry price of $0.35, this is a rare opportunity to secure early access to what many are calling the year’s most powerful utility asset. Early participants can join simultaneously on MultiBank.io, the Group’s regulated crypto exchange, and Uniswap, the world’s leading decentralized platform. Supported by $29 billion in real assets and powered by over $35 billion in daily turnover, $MBG is engineered
Live Story Raises €2.7 Million to Revolutionize the Digital Experience11.7.2025 10:05:00 CEST | Press release
With a round led by Vertis, the next-generation CMS platform accelerates its focus onAI, performance, and European expansion. Target: surpass €10M in recurring revenueby 2027. Live Story, the tech company founded by Stefano Mocellini, has closed a €2.7 million seed round led by Vertis, one of Italy’s leading early-growth venture capital firms. The funding will support the company’s international expansion and technological development, with a clear goal: to exceed €10 million in annual recurringrevenue by 2027. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250711335560/en/ “We invested in Live Story because it addresses one of the major inefficiencies in digital commerce: the slow and rigid management of visual and narrative content,” says Alessandro Pontari, Partner at Vertis SGR. “The platform helps brands drastically reduce their time-to-market through a visual CMS that integrates seamlessly with any tech stack. In a wor
With a Score of 84 out of 100, Sagemcom Is Awarded the EcoVadis Platinum Medal: a Prestigious Recognition of its CSR Commitment11.7.2025 09:00:00 CEST | Press release
Sagemcom Group is proud to announce that it has been awarded, for the third time, the Platinum Medal by EcoVadis, the highest distinction granted by the leading global platform for assessing Corporate Social Responsibility (CSR) performance. This medal places Sagemcom in the top 1% of companies evaluated worldwide, across all industries. With a score of 84 out of 100, Sagemcom reaffirms its position as a committed leader in ecological transition, business ethics, sustainable supply chain management, and social responsibility. “The EcoVadis Platinum Medal is more than just an award — it is the recognition of our collective efforts to embed sustainable development principles at the heart of our corporate strategy and culture,” says Sylvaine Couleur, Executive Vice President, CSR & Communication. “Achieving this level demonstrates that our commitments are tangible, impactful, and internationally recognized. This distinction strengthens our determination to further advance and expand our C
IEEE Standards Commitment to Advancing AI Governance Includes Impactful Contributions to New International AI Standards Exchange11.7.2025 08:00:00 CEST | Press release
IEEE, the world’s largest technical professional organization dedicated to advancing technology for humanity, and its IEEE Standards Association (IEEE SA) announced today that its portfolio of over 100 global AI-related standards is included in the new International AI Standards Exchange. This Exchange is a centralized repository of international AI standards with the aim to foster collaboration and responsible AI development worldwide. IEEE and its AI global standards were recognized in the 2024 United Nations AI Advisory Body’s Report, Governing AI for Humanity, which created the impetus for the AI Standards Exchange. Due to its impactful AI standards and related work, IEEE, a major standards body, was included as a partner in the establishment of the Exchange. IEEE President and CEO Kathleen Kramer, who is speaking at the AI for Good Summit this year at the High-Level AI Standards Panel,shares, “IEEE’s mission of advancing technology for the benefit of humanity is foundational to ou
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom