BIOCAD
In March 2018, BIOCAD analyzed results from its Phase II study in which the original Russian IL-17 inhibitor proved highly effective in long-term therapy in patients with severe psoriasis. The drug also showed great results in the treatment of ankylosing spondylitis.
BCD-085 is an original monoclonal antibody drug blocking interleukin-17, a cytokine playing a key role in developing and maintaining various autoimmune and immunoinflammatory diseases.
The majority of psoriasis patients have serious psychological problems due to social isolation, while patients with ankylosing spondylitis may rapidly become disabled if diagnosed late or treated inappropriately. Both diseases are a serious medical and social challenge, especially because they often affect young people of working age (22 to 35 years old). The European market of IL-17 inhibitors is over $700 million and it’s going to grow to $1 677 million within next 5 years. BIOCAD expects to occupy an essential share of this perspective market.
BCD-085 has demonstrated extremely high efficacy in the recently completed Phase II clinical study. Over the first three months of treatment with Interleukin-17 inhibitor at a dose of 120 mg, significant clinical response (PASI 75) was achieved in 93% of patients with moderate to severe psoriasis who did not respond to conventional treatments. Similar improvements were seen in patients with ankylosing spondylitis who were treated with IL-17 inhibitor 120 mg: 91% of patients demonstrated clinical improvements (ASAS20) after 4 months of treatment.
Оne-year treatment with this IL-17 inhibitor resulted in a sustained improvement in psoriasis symptoms (PASI 75) in 98% of cases, with over 50% of patients having an sPGA score of 0 or 1 at the end of the observation, which refers to almost complete skin clearance. High efficacy of BCD-085 comes along with a favorable safety profile:
‘IL-17 inhibitor is a rare example of a monoclonal antibody used for the treatment of chronic diseases that has such a beneficial efficacy and safety profile,’ says Roman Ivanov, M.D., PhD, BIOCAD’s Vice-President of Research and Development. ‘We have a good reason to believe that BCD-085 will become the best-in-class interleukin-17 inhibitor. This is why we are going to initiate a phase III study in the European Union in 2019; in this study, we will compare our product head-to-head with another IL-17 inhibitor.’
View source version on businesswire.com: https://www.businesswire.com/news/home/20180426005673/en/
Contact:
BIOCAD
Irina Kenyukhova
Head of PR Department
Tel.:
+7(812)3804933, ext. 632
+7(921)3760577
E-mail: kenyukhova@biocad.ru
Link:
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
VT-CANNATROL25.4.2024 14:04:26 CEST | Press release
Cannatrol, Creators of Breakthrough Postharvest Cannabis Technology, Receive Two European Patent Approvals
CA-VISA25.4.2024 14:01:36 CEST | Press release
Visa Joins AWS Partner Network to Help Simplify Global Digital Payments
AZ-EDGIO25.4.2024 14:01:25 CEST | Press release
Edgio Releases Client-Side Protection to Help Protect Users’ Data Against Malicious Scripts
AMRA-MEDICAL25.4.2024 13:51:35 CEST | Press release
Baseline Enrollment Completed for AMRA Medical and Linköping University’s Landmark Liver Disease Study
MA-NETSCOUT-SYSTEMS25.4.2024 12:06:33 CEST | Press release
Geopolitical Unrest Generates an Onslaught of DDoS Attacks, According to the Latest NETSCOUT Threat Intelligence Report
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom