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Apricus Biosciences, Inc.

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CORRECTING and REPLACING -- Apricus Biosciences to Host Live Webcast KOL Event on May 9th Addressing Vitaros® and Erectile Dysfunction Population

In a release issued under the same headline earlier today by Apricus Biosciences, Inc. (Nasdaq:APRI), please note that in the second line of the subheadof the release, "2H 2016"should instead be "Q32016."

The corrected release follows:

Presentation Speaker will be Edward D. Kim, M.D., Professor, The University of Tennessee Graduate School of Medicine

Vitaros U.S. NDA Re-Submission Remains on Schedule for Q32016

SAN DIEGO, May 03, 2016 (GLOBE NEWSWIRE) -- Apricus Biosciences, Inc. (Nasdaq:APRI), a biopharmaceutical company advancing innovative medicines in urology and rheumatology, today announced it will host a Vitaros®and erectile dysfunction (“ED”) key opinion leader event on Monday, May 9th, from 11:00 a.m. to 12:00 noon ET.

The meeting will feature a presentation by Edward D. Kim, M.D., Professor, Division of Urology at The University of Tennessee Graduate School of Medicine, Knoxville, TN. Dr. Kim will address the current status of treatment options in the ED population, unmet patient need based on contraindications or suboptimal response to currently available systemic treatments, provide an overview of the clinical data for Vitaros, and discuss where a non-systemic, topical treatment in the ED patient population may add value.

A live webcast with presentation slides and subsequent replay of the event will be available atwww.apricusbio.com. If you would like to ask a question during the live Q&A, please submit your request via email tombeck@troutgroup.com. Please log in approximately 5-10 minutes before the event to ensure a timely connection. To participate by telephone, please dial (877) 841-3961 (Domestic) or (201) 689-8589 (International). The conference ID number is 13633850. The archived webcast will remain available for 30 days following the live presentation.

About Apricus Biosciences, Inc.

Apricus Biosciences, Inc. (APRI) is a biopharmaceutical company advancing innovative medicines in urology and rheumatology. Apricus’ commercial product, Vitaros®, for the treatment of erectile dysfunction, is approved in Europe and Canada and is being commercialized in several countries in Europe. In September 2015, Apricus in-licensed the U.S. development and commercialization rights for Vitaros from Allergan. Apricus’ marketing partners for Vitaros include Laboratoires Majorelle, Bracco S.p.A., Hexal AG (Sandoz), Recordati Ireland Ltd. (Recordati S.p.A.), Ferring International Center S.A. (Ferring Pharmaceuticals), Mylan NV and Elis Pharmaceuticals Ltd. Apricus currently has one active product candidate, RayVa™, its product candidate for the treatment of the circulatory disorder Raynaud’s phenomenon.
For further information on Apricus, visithttp://www.apricusbio.com.

*Vitaros®is a registered trademark of NexMed International Limited. Such trademark is registered in certain countries throughout the world and pending registration in the United States.

CONTACT: Institutional / Retail Investors: Matthew Beck
mbeck@troutgroup.com
The Trout Group LLC
(646) 378-2933

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