RELIEF-THERAPEUTICS
Relief Therapeutics a Swiss-based, privately owned startup company announced today an in-licensing agreement from Merck Serono, the biopharmaceutical business of Merck, Darmstadt, Germany, giving Relief Therapeutics the worldwide exclusive rights to develop and commercialize atexakin alfa. Financial terms were not disclosed.
Under the terms of the agreement, Relief Therapeutics will develop atexakin alfa for the treatment of neuropathies. Atexakin alfa has the potential of relieving pain, as well as non-pain symptoms associated with neuropathies by restoring normal innervation in the periphery.
“This agreement constitutes a great opportunity to develop the first disease modifying treatment that has the potential to significantly reduce the burden of neuropathies to patients, care givers and society,” said Dr. Gael Hédou, co-founder of Relief Therapeutics.
About Atexakin alfa
Atexakin alfa is a human recombinant version of interleukin-6 that has shown in preclinical studies to induce the re-growth of nerves and to re-establish normal nerve conduction and sensory perception in various relevant animal models of neuropathies. Initially discovered at the Weizmann institute (IL), this molecule was first tested as a potential treatment for thrombocytopenia in chemotherapy-treated cancer patients allowing the delineation of its safety and pharmacodynamic profiles. Based on positive preclinical, toxicological and clinical data obtained at this time, Relief Therapeutics will engage into clinical development to test the therapeutic efficacy of atexakin alfa in diabetic patients suffering from neuropathy.
About Peripheral Neuropathies
Peripheral neuropathies are a group of conditions characterized by degeneration of peripheral motor, sensory, or autonomic nerves. Degeneration of peripheral nerves causes a wide variety of symptoms and signs ranging from intractable pain, numbness and tingling to potentially impairment of strength, balance, and coordination. Neuropathies develop as a result of toxic, inflammatory, infectious, genetic, neoplastic, and metabolic diseases. Medications, particularly chemotherapy are also a common cause. In the case of diabetic neuropathy, half of the diabetic population worldwide becomes affected during the course of their disease. Quality of life is heavily affected in patients with neuropathy and the costs associated with medical care and lost wages is substantial. There are very few therapies available to patients suffering from these disorders and treatments are often associated with side effects limiting their use. Furthermore, no treatment truly stops or reverses neuropathy. Atexakin alfa has the potential to restore nerve function and potentially alleviate painful and non-pain-related symptoms.
About Relief Therapeutics
Relief Therapeutics is a privately owned startup company based in Geneva, Switzerland, incorporated in 2013. Relief Therapeutics is committed to develop new treatments for diseases with high unmet needs and significant burden on patients’ quality of life and society.
This news release contains forward-looking statements that are subject to known and unknown risks and uncertainties causing results to potentially differ from the statements made. Relief Therapeutics and Merck Serono cannot be taken responsible in any manner if such statements are not verified in the future.
View source version on businesswire.com: http://www.businesswire.com/news/home/20150907005042/en/
Contact:
Relief Therapeutics
Dr. Gael Hédou
gael.hedou@relieftherapeutics.com
tel:+41
79 457 0937
Link:
Information om Business Wire
Følg pressemeddelelser fra Business Wire
Skriv dig op her, og modtag pressemeddelelser på e-mail. Indtast din e-mail, klik på abonner, og følg instruktionerne i den udsendte e-mail.
Flere pressemeddelelser fra Business Wire
Everen Specialty Appoints Carla Greaves Chief Underwriting Officer25.4.2025 19:00:00 CEST | Press release
Everen Specialty, a Bermuda-based (re)insurer for energy markets worldwide, today announced the appointment of Carla Greaves as its new Chief Underwriting Officer (CUO). This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250425273777/en/ Carla Greaves Ms. Greaves will join the Executive Leadership Team of the Everen Group, based in the Bermuda office, later this year. She succeeds Jane Peterson, Interim CUO, who will continue in a consultancy capacity to facilitate the transition. With more than 30 years of underwriting and leadership experience in the (re)insurance industry, Ms. Greaves brings a wealth of expertise and a proven track record of success in the Casualty market where she is recognized for building high-performing teams, driving profitable growth, and successfully navigating complex market environments. Prior to joining Everen Specialty, Ms. Greaves held increasingly senior leadership positions, most recently servin
Incyte to Highlight Early-Stage Oncology Data at American Association for Cancer Research Annual Meeting 202525.4.2025 14:00:00 CEST | Press release
Incyte (Nasdaq:INCY) today announced that the Company will present new early-stage data from its oncology portfolio at the American Association of Cancer Research (AACR) Annual Meeting 2025 in Chicago, IL, from April 25–30. “At AACR we will be presenting data from early-stage programs across our oncology portfolio, including for patients with myeloproliferative neoplasms, ovarian cancer and other solid tumors,” said Pablo J. Cagnoni, M.D., President and Head of Research and Development, Incyte. “These data will guide our approach as we advance our pipeline and seek to transform the treatment landscape for patients with cancer and myeloproliferative neoplasms.” Abstracts accepted for presentation at AACR include: Mini Symposium INCB177054 INCB177054: A Novel, Potent, Orally Bioavailable DGKα/ζ Dual Inhibitor Enhances T-Cell Function and Demonstrates Potent Antitumor Activity (Session Title: Novel Antitumor Agents. April 28, 4:50 p.m. – 5:05 p.m. ET (3:50 p.m. – 4:05 p.m. CT). Abstract #
SLB Announces First-Quarter 2025 Results; Remains Committed to Return a Minimum of $4 Billion to Shareholders in 202525.4.2025 12:50:00 CEST | Press release
Revenue of $8.49 billion decreased 3% year on year GAAP EPS of $0.58 decreased 22% year on year EPS, excluding charges and credits, of $0.72 decreased 4% year on year Net income attributable to SLB of $797 million decreased 25% year on year Adjusted EBITDA of $2.02 billion decreased 2% year on year Cash flow from operations of $660 million increased $333 million year on year Board approved quarterly cash dividend of $0.285 per share SLB (NYSE: SLB) today announced results for the first-quarter 2025. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250423635499/en/ The exterior of the SLB headquarters in Houston, Texas. First-Quarter Results (Stated in millions, except per share amounts) Three Months EndedChange Mar. 31, 2025 Dec. 31, 2024 Mar. 31, 2024 Sequential Year-on-year Revenue $8,490 $9,284 $8,707 -9% -3% Income before taxes - GAAP basis $1,063 $1,387 $1,357 -23% -22% Income before taxes margin - GAAP basis 12.5% 14.9%
Corona, The World’s Most Valuable Beer Brand1, Announces Its 100-Year Anniversary with Global Celebration25.4.2025 10:00:00 CEST | Press release
Brand Invites The World to Join the Celebration with Experiences at the Most Epic Beaches on EarthGlobal “Corona 100” Platform Launches with a Legendary Concert at Copacabana Beach, Featuring One of the World’s Top Musical Artists with Millions in Attendance Today, Corona proudly celebrates its 100-year anniversary, a remarkable milestone for the iconic brand that has been synonymous with the beach and enjoyed by consumers worldwide for the past century. Since 1925, Corona has cultivated a deep association with the beach; fully embodying a lifestyle connected to nature and relaxation. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250425804516/en/ Corona 100 This Is Living Since 1925 In honor of the occasion, Corona invites everyone to live their “beach side” – a.k.a. their best side – at top-tier beach locations across the globe. The Corona 100 platform includes a film highlighting 100 years of beach culture, a definitive l
Ant Group Unveils New Recruitment Initiative for Top AI Talents, Ramping Up AI Innovation Efforts25.4.2025 09:28:00 CEST | Press release
Ant Group today unveiled Plan A, a new recruitment initiative to attract top artificial intelligence researchers, reinforcing its commitment to accelerating AI research and development under the “AI First” corporate strategy. Operating within the framework of Ant Star—Ant Group’s year-round campus recruitment program—Plan A specifically targets AI talents who are ambitious, adaptable, altruistic, and analytical. Outstanding graduates from universities worldwide with STEM majors are encouraged to apply for Plan A. Relevant fields include computer science, software engineering, artificial intelligence, cybersecurity, information and telecommunication engineering, mathematics, statistics, and other emerging interdisciplinary areas. To better foster the development of technological innovators in this new AI era, Plan A offers candidates comprehensive support and resources, including unrestricted access to AI hardware and tailored career paths that allow for significant research freedom. Ad
I vores nyhedsrum kan du læse alle vores pressemeddelelser, tilgå materiale i form af billeder og dokumenter samt finde vores kontaktoplysninger.
Besøg vores nyhedsrum