TriLink BioTechnologies® and Aldevron Enter into Non-exclusive License and Supply Agreement for CleanCap® mRNA Capping Technology
Enabling the future development of critical therapeutics, Aldevron customers now have access to TriLink’s CleanCap mRNA capping technology for non-commercial use
TriLink BioTechnologies (TriLink®), a Maravai® LifeSciences company (NASDAQ: MRVI) and global provider of life science reagents and services, has signed a non-exclusive License and Supply Agreement with Aldevron, a leading, global Contract Development and Manufacturing Organization (CDMO) providing high-quality plasmid DNA, RNA, and proteins for research, therapeutics, and diagnostics. With this agreement with Aldevron, TriLink strengthens its objective to provide greater access to CleanCap® mRNA capping technologies to those developing critical mRNA-based therapeutics and vaccines.
According to the terms of the agreement, TriLink will supply its patented CleanCap® M6, CleanCap® AG 3’OMe, CleanCap® AG, and CleanCap® AU cap analogs for use in Aldevron’s mRNA development and manufacturing services, from pre-clinical through Phase III programs. CleanCap® technology produces optimal 5’Cap structures with over 95% efficiency, creating a co-transcriptional capping solution that improves mRNA yield and process time when compared to legacy capping methods.
“CleanCap technology is accelerating programs through drug development milestones and has been the capping technology of choice for mRNA constructs in 350+ preclinical and clinical programs,” shared Becky Buzzeo, Chief Commercial Officer, Maravai. “We’re excited to offer our innovative capping solutions to Aldevron and its manufacturing customers.”
Since its launch in 2017, TriLink’s CleanCap® capping technology has continued to advance the mRNA capping industry and is used in the majority of all approved COVID-19 mRNA and saRNA vaccines. In May 2023, TriLink introduced its most robust CleanCap® analog to date, CleanCap® M6, with studies indicating increased mRNA expression by more than 30% versus enzymatic capping methods.
Aldevron, based in Fargo, ND, is a leader in advancing biological science. Their custom development and manufacturing services provide scientists with essential components to accelerate research and breakthrough discoveries.
About TriLink BioTechnologies
TriLink BioTechnologies, a Maravai LifeSciences company, is a global leader in nucleic acid and mRNA solutions. TriLink delivers unrivaled chemical and biological experience, CDMO services, and high-quality readymade and custom materials, including its patented CleanCap® mRNA capping technology. Pharmaceutical leaders, biotech disruptors, and world governments depend on TriLink to meet their greatest challenges, from delivering the COVID-19 vaccine at warp speed to empowering innovative treatments in oncology, infectious diseases, cardiology, and neurological disorders to enabling future pandemic response plans.
For more information, visit trilinkbiotech.com.
About Maravai LifeSciences
Maravai is a leading life sciences company providing critical products to enable the development of drug therapies, diagnostics, and novel vaccines. Maravai’s companies are leaders in providing products and services in the fields of nucleic acid synthesis and biologics safety testing to many of the world’s leading biopharmaceutical, vaccine, diagnostics, and cell and gene therapy companies.
For more information about Maravai LifeSciences, visit maravai.com.
About Aldevron
Aldevron is a premier manufacturing partner, producing high-quality plasmid DNA, RNA, proteins, enzymes, and other key components for the development of vaccines, gene and cell therapies, immunotherapies, and other treatments. Headquartered in Fargo, North Dakota, and as a part of the Danaher Corporation (NYSE: DHR) family of global science and technology companies, Aldevron supports thousands of scientists who are developing revolutionary, lifesaving treatments for millions of people. To learn more about how Aldevron is advancing biological science, visit www.aldevron.com.
View source version on businesswire.com: https://www.businesswire.com/news/home/20250204333920/en/
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Hitachi Establishes Its Fourth Corporate Venture Capital Fund to Capture Technology Turning Points and Future Growth Opportunities5.2.2025 07:00:00 CET | Press release
Total Assets Under Management (AUM) Reaches 1 Billion USD, Contributing to Sustainable Growth with a World-Class Investment Scale Hitachi, Ltd. (TSE: 6501, "Hitachi") today announced the establishment of the fourth fund of the corporate venture capital (hereinafter referred to as "CVC") fund"HV Fund" with a purpose to identify startups with the potential to create or disrupt large attractive markets, anticipate the next technological and social turning points, and generate future growth opportunities. The fourth fund will have a size of 400 million USD, which is the largest CVC fund managed by Hitachi to date. The fund will make strategic investments in startups with cutting-edge digital technologies such as data centers, distributed energy systems, future of work and industrial AI, as well as startups in new frontiers including bio, quantum, nuclear fusion, life science, space and adjacent technologies. With the establishment of the fourth fund, Hitachi's investment in CVC will reach
Telcoin Granted Approval to Open Nebraska’s First Digital Asset Bank4.2.2025 20:32:00 CET | Press release
Regulators give green light for first regulated bank explicitly authorized to connect US consumers to decentralized finance, ushering in a new era of blockchain-integrated banking. Telcoin, a pioneer in blockchain-based financial services, announced that its application to become Nebraska’s first Digital Asset Depository Institution has been conditionally approved by the state’s Department of Banking and Finance. This approval brings Telcoin Bank, a Digital Asset Bank, another step closer to creating the first real bridge between traditional finance and cryptocurrencies. Telcoin Bank is now poised to become the first regulated crypto bank in the United States. Its upcoming launch is expected to disrupt the US$200 billion stablecoin market and transform the financial landscape by offering fully regulated, bank-issued “Digital Cash” stablecoins, as well as an innovative suite of blockchain banking products and services. This development promises to accelerate the adoption of crypto in ma
HTEC and AI Inference Hardware Startup, d-Matrix, Announce Strategic Partnership4.2.2025 19:23:00 CET | Press release
HTEC, a global consulting, software, and digital product development company, is proud to announce a strategic partnership with d-Matrix, the creator of Corsair™, the world’s most efficient AI computing platform for inference in datacenters. HTEC Advisory Board member Sasha Ostojic, who also sits on d-Matrix's Board of Directors, was instrumental in connecting the companies and expediting the collaboration. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250204571709/en/ HTEC announces partnership with d-Matrix, the creator of Corsair™, the world’s most efficient AI computing platform for inference in datacenters (Graphic: Business Wire) During their work together, HTEC will leverage its extensive expertise in AI and embedded software development to support d-Matrix in the development of its software solution. Additionally,HTEC will use an active management approach to proactively identify and address issues and robust report
Monroe Capital Hires Galen Fu as Director, Business Development and Opens Australia Office4.2.2025 17:00:00 CET | Press release
Monroe Capital LLC (“Monroe”) today announced it has expanded its platform to Australia with the appointment of Galen Fu as Director, Business Development. Fu will be based in the firm’s Sydney, Australia office and will be responsible for client servicing and capital raising across Australia. Fu has more than 14 years of experience in capital raising, portfolio management and banking in the Asia-Pacific region. Prior to Monroe, he was a Director in the Capital Markets team at Hines Investment Management where he was responsible for business development and investor relations across Australia. He previously held roles at MaxCap Investment Management (a subsidiary of Apollo Global Management), Westpac Bank and ANZ Bank. Fu earned his B.A. in Commerce and Economics from the University of New South Wales. “We have several long-standing limited partners in Australia and we look forward to our continued strategic growth and expansion in Australia,” said Zia Uddin, President of Monroe Capita
NTT DATA, Inc. Appoints Sudhir Chaturvedi as Global Chief Growth Officer and North America CEO4.2.2025 17:00:00 CET | Press release
NTT DATA, a global digital business and IT services leader, today announced that Sudhir Chaturvedi will join NTT DATA, Inc. as its Global Chief Growth Officer and North America Chief Executive Officer. In the newly created Global Chief Growth Officer role, Chaturvedi will lead the acceleration of consistent growth strategies globally, with special focus on global industries, strategic accounts, and joint go-to-market execution with key strategic partners. In his North America CEO role, Chaturvedi will lead NTT DATA Inc.’s growth and business in this strategic region, while leveraging synergies with his Global Chief Growth Officer remit. Chaturvedi succeeds Eric Clark who is leaving the company for a leadership role outside of NTT DATA. Chaturvedi will report to Abhijit Dubey, President and Global CEO of NTT DATA, Inc., and plans to be based in Plano, TX. “Sudhir has a unique blend of expertise across Consulting, IT Services and Software, alongside industry, digital transformation and s
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom