ProteinQure to Present Data on PQ203, a Novel Peptide-Drug Conjugate for Triple Negative Breast Cancer, at 2024 San Antonio Breast Cancer Symposium
6.12.2024 12:30:00 CET | ACCESS Newswire | Press release
TORONTO, ON / ACCESSWIRE / December 6, 2024 / ProteinQure, the leading company in computational design of peptide therapeutics, will be presenting compelling new data on the progress of their lead triple negative breast cancer (TNBC) drug PQ203 (December 12, 2024 presentation ID: P4-12-17) at the 2024 San Antonio Breast Cancer Symposium.
PQ203 is a novel Peptide Drug Conjugate composed of a Sortilin receptor targeting peptide conjugated to the cytotoxic agent monomethyl auristatin E. The Sortiin receptor is expressed in a high percentage of diseased tissue from TNBC patients and as such represents an innovative treatment for this challenging sub-type of breast cancer.
ProteinQure has recently generated data that PQ203 exhibits potent efficacy in a patient-derived xenograft (PDX) model resistant to Sacituzumab Govitecan (Trodelvy™), an antibody drug conjugate that is the emerging standard of care for metastatic TNBC. Additionally, PQ203 has shown an encouraging safety profile. Based on these findings as well as earlier in vivo efficacy studies, ProteinQure has initiated GLP-toxicology studies for PQ203 in support of an anticipated investigational new drug application filing in Q2 of 2025.
"These combined findings confirm the power of our computational drug design platform and its potential to address key challenges in cancer therapy. We are deeply committed to moving PQ203 forward and are eager to bring this innovative treatment to clinical trials." stated Lucas Siow, CEO of ProteinQure.
Phase 1a/b trial initiation for PQ203 is planned for the second half of 2025 and will be coordinated at the Princess Margaret Cancer Center in Toronto and other leading hospitals in North America.
For media inquiries please contact Lucas Siow at lucas@proteinqure.com
SOUCE: ProteinQure Inc.
View the original press release on accesswire.com
ProteinQure Inc.
Subscribe to releases from ACCESS Newswire
Subscribe to all the latest releases from ACCESS Newswire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from ACCESS Newswire
Crossmint Secures Payment Institution and MiCA Authorization, Completing a Full-Stack EU Regulatory Stack for Stablecoin Payments3.7.2026 21:00:00 CEST | Press release
With Authorization as a Crypto-Asset Service Provider Under MiCA and Payment Institution Under PSD2, Crossmint Now Operates Under Both of the EU's Core Frameworks for Stablecoin Infrastructure, Giving Enterprise Fintechs One Regulated Provider to Hold Stablecoins and Move Them as Payments MADRID, ES / ACCESS Newswire / July 3, 2026 / Crossmint has been authorized as a Payment Institution (PI) by the Bank of Spain under the EU's Payment Services Directive (PSD2). Earlier this year, Crossmint received MiCA class 2 authorization from Spain's CNMV, establishing complete authorization to operate as a crypto-asset service provider across the EU. After completing the required conditions, Crossmint has now successfully been fully registered as a CASP with CNMV, which allows passporting across all 27 EU member states. PSD2 authorization is the natural expansion of that compliance footprint, enabling stablecoins to be used as a means of payment under EU payments law. "Crossmint's mission is to b
Polaris Renewable Energy Announces Q2 2026 Investor Call Details3.7.2026 19:30:00 CEST | Press release
TORONTO, ON / ACCESS Newswire / July 3, 2026 / Polaris Renewable Energy Inc. (TSX:PIF) ("Polaris" or the "Company") is pleased to announce it will be holding its Earnings Conference Call and Webcast to report its Q2 2026 Earnings Results on Thursday, July 30th, 2026, at 10:00 am EST. To listen to the call, please dial Toll Free 1 888-506-0062 or International Toll-Free Number 973-528-0011 entry code 503447 or URL: https://www.webcaster5.com/Webcast/Page/2773/53517 A digital recording of the earnings call will be available for replay two hours after the call's completion. Replay Call Information: Toronto: 1 877-481-4010, Passcode: 53517 International (toll-free): 1 919-882-2331, Passcode: 53517 Encore Replay Expiration Date: August 13, 2026 About Polaris Renewable Energy Inc. Polaris Renewable Energy Inc. is a Canadian publicly traded company engaged in the acquisition, development, and operation of renewable energy projects in Latin America and the Caribbean. We are a high-performing a
GoodData.AI Recognized in 2026 Gartner(R) Magic Quadrant(TM) for Analytics and BI Platforms2.7.2026 14:05:00 CEST | Press release
GoodData.AI positioned as a Visionary by Gartner® for completeness of vision and ability to execute. SAN FRANCISCO, CA / ACCESS Newswire / July 2, 2026 / GoodData.AI, the AI-native analytics platform, today announced its recognition as a Visionary in the 2026 Gartner® Magic Quadrant™ for Analytics and Business Intelligence Platforms. For GoodData.AI, this recognition marks a significant milestone, reflecting its journey of recognition from a Niche Player to a Visionary - a testament to the company's continued investment in its composable, AI-native analytics architecture and the growing enterprise demand for developer-centric, embedded analytics at scale. At the heart of GoodData.AI's platform is a headless semantic layer that serves as the governed foundation for business intelligence, data science, AI agents, and embedded application experiences. The platform's analytics-as-code approach enables development teams to build, automate and govern analytics like any other software compone
U.S. Polo Assn. Celebrates 250 Years of American Spirit and Collaborates with ESPN on 'Polo in America' Broadcast Special2.7.2026 13:00:00 CEST | Press release
Global sports brand commemorates enduring connection between sport and American culture WEST PALM BEACH, FL / ACCESS Newswire / July 2, 2026 / U.S. Polo Assn.®, the official sports brand of the United States Polo Association (USPA), proudly marks America's 250th Anniversary with a celebration of the nation's enduring spirit - one rooted in sport, heritage, and a distinctly American sense of style. To highlight the connection between U.S. Polo Assn. and the sport of polo, the brand is collaborating with ESPN on a 30-minute broadcast special, 'Breakaway: Polo in America.' The award-winning Breakaway Series will produce a special episode to give audiences an inside look at the long history and significant impact the sport of polo has had on America over the past century. This episode will broadcast globally on ESPN and on Global Polo's YouTube. Founded in 1890, the USPA is one of the oldest national governing bodies for sport in the United States, and U.S. Polo Assn. carries that legacy f
The Inaugural Michelin Guide New Zealand Reveals 1 Two Michelin Stars, 14 One Michelin Star And 35 Bib Gourmands1.7.2026 23:40:00 CEST | Press release
AUCKLAND, NZ / ACCESS Newswire / July 1, 2026 / The inaugural MICHELIN Guide New Zealand 2026 has recognised 110 restaurants across Auckland, Wellington, Christchurch and Queenstown, celebrating exceptional quality, creativity and a strong sense of place. After months of anonymous inspections, the MICHELIN Guide has awarded one restaurant in Queenstown, Essence, Two MICHELIN Stars. Fourteen restaurants have received One MICHELIN Star, 35 have been recognised with a Bib Gourmand for offering good food at great value, and a further 60 are included in the official MICHELIN Guide selection. Gwendal Poullennec, International Director of the MICHELIN Guide, said: "It is rare to award such a quantity of Stars in a country's inaugural launch, New Zealand's performance has been genuinely impressive. The destination presents more than a selection of outstanding restaurants; to our Inspectors, it revealed a contemporary culinary map shaped by unique terroir and a food culture in quiet harmony wit
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom