PK-MED
PK MED, a French biotech company, privately owned, and established in 2019 by Truffle Capital, announced it has secured a non-dilutive DeepTech financing of € 1.5 million from Bpifrance. The funding will accelerate the company’s project PKM-02, an innovative cell-homing technology aiming to enhance bone marrow transplantation in several diseases with high unmet medical need, such as leukemias and hemoglobinopathies.
Allogenic Hematopoietic Stem Cell Transplantation (HSCT), also known as bone marrow transplantation, involves transferring hematopoietic stem cells from a healthy donor to a patient with depleted or dysfunctional bone marrow. In a broad range of hematologic disorders, this therapy can be curative and/or prolong a patient’s life. More than 25,000 allogenic HSCTs are performed per year in the US and EU, and the treatment’s success depends on sufficient hematopoietic stem cell seeding, engraftment, and expansion within the bone marrow of the patient. However, the fraction of transplanted cells able to make their way to the bone marrow, known as homing, is reported to be low (1-10%). In addition, many patients are not eligible for the procedure, due to limited donor matching and an aggressive conditioning regimen needed to obtain a successful engraftment of the donor cells. Thus, there is an urgent unmet medical need to enhance the homing and engraftment of the transplanted cells.
PK MED’s innovative approach for this PKM-02 project, is based on the development of a therapeutic implant locally injected into the patient's bone marrow prior to allogeneic HSCT. This drug-based unique technology, combined with a biodegradable scaffold, is aimed at increasing the homing of the transplanted cells, as well as their subsequent engraftment. PKM-02 has shown several promising in vitro results, and PK MED is currently initiating preclinical studies. PK MED is considering extending this innovative technology to other applications in tissue regeneration.
Gauthier Pouliquen, Ph.D., CEO of PK MED, comments: “The development of our local cell-homing implant and the support of Bpifrance are a proof of PK MED's technological excellence and its commitment to medicine. Our ambition is to significantly advance bone marrow transplantation and cell regeneration techniques, for the benefit of all patients with hematologic disorders.”
About PK MED
PK MED is a French biotechnology company, founded in 2019 by Truffle Capital, developing injectable smart implants for drug release in rheumatology and cell homing for bone marrow transplantation. PK MED's unique expertise and technological know-how enable evolving existing systemic treatments into new, safer and more effective patented local therapies.
PK MED has developed a portfolio of projects in indications where medical needs are high, starting with gout (PKM-01) and Hematopoietic Stem Cells transplants (PKM-02).
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
View source version on businesswire.com: https://www.businesswire.com/news/home/20240724252487/en/
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Network Failures Cost $5M A Year for More Than a Quarter of Global Businesses, According to Expereo1.7.2025 10:00:00 CEST | Press release
Half of global businesses have been forced to urgently re-evaluate their tech infrastructure following a wave of high-profile IT outages Network instability is taking a serious toll on global businesses, with over a quarter (28%) reporting revenue losses of up to $5 million due to network outages or poor performance. Alarmingly, an additional 23% have experienced losses exceeding $5 million. These findings come from an IDC InfoBrief commissioned by Expereo, titled “Enterprise Horizons 2025: Technology Leaders Priorities: Achieving Digital Agility.” Following a series of high-profile IT disruptions over the past year, ranging from cybersecurity breaches to connectivity failures, nearly half (49%) of global businesses have been compelled to re-evaluate their technology infrastructure, and 40% of global tech leaders say it’s caused networking and connectivity to rise higher up the C-suite agenda. Perhaps as a result, networking/connectivity now comes out on top in terms of the technologie
Record Financing for NeXtWind: €1.4 Billion for the Expansion of Wind Energy in Germany1.7.2025 09:52:00 CEST | Press release
Innovative platform financing enables debt investments in renewable energy on an unprecedented scale NeXtWind plans to quadruple the capacity of more than half of its 37 wind farms by 2028 as part of an increase of its total generation capacity to 3 GW Lars B. Meyer, Co-CEO of NeXtWind, said: “Thanks to this novel platform approach, we can optimize our wind farms more quickly and accelerate our growth. In the long term, we aim to transform them into state-of-the-art, integrated clean energy hubs.” NeXtWind, a leading renewable energy company, has secured €1.4 billion in debt financing. The agreement also includes an additional €1.3 billion in so-called accordion facilities, which can be activated in tranches over the coming years. This syndicated loan is the largest of its kind for an independent wind energy provider in Germany, and it opens the onshore wind market to debt investments from major financial institutions both domestically and internationally. NeXtWind will use the new fin
Celero Ventures Opens $25 Million Early-Stage Fund to Investors Backing the Next Generation of European Software Companies1.7.2025 09:30:00 CEST | Press release
Celero Ventures, a new venture capital firm founded by experienced software operators Dave Wyatt and Nick Cochran, is now raising its debut $25 million fund to invest in early-stage startups across the UK and Europe. The fund, which is already 25% subscribed, targets pre-seed and seed-stage companies building next-generation AI and data infrastructure. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250701820933/en/ Nick Cochran and David Wyatt (right) Founders of Celero Ventures Based in London, Celero Ventures is inviting limited partners (LPs) to join its mission of backing exceptional technical founders and accelerating their path to product-market fit and scalable growth. Wyatt and Cochran bring a rare combination of deep go-to-market (GTM) experience and startup leadership. Together, they helped scale both MuleSoft and Databricks—two of the most successful enterprise software companies of the past decade. Their experien
3GPP MCX Standards-Based Hytera HyTalk MC 6.0 Released Globally1.7.2025 09:00:00 CEST | Press release
Hytera, a leading global provider of professional communications technologies and solutions, announced the worldwide release of Hytera HyTalk MC 6.0, its new-generation broadband mission-critical communication platform fully compliant with the 3GPP MCX standard Release 18. As a key part of Hytera’s convergence-native communications strategy, it delivers inclusive, efficient and secure communication over LTE cellular network. Hytera HyTalk MC 6.0 leverages 3GPP standard interfaces and Hytera’s proprietary protocols to enable deep interworking across different technologies and vendors. It enables real-time mapping between the signaling of 3GPP MCX and Hytera DMR, and interconnects with HyteraTETRA systems, allowing a smooth migration path to data-rich communications for mission- and business-critical institutions and users. Hytera DMR or TETRA two-way radios can communicate with LTE/5G terminals through the Hytera HyTalk MC platform in a hybrid network. The Ad-Hoc Temporary Group Call fe
Lyten Acquires Europe’s Largest Battery Energy Storage Systems Manufacturing Operation from Northvolt1.7.2025 09:00:00 CEST | Press release
Lyten will take full ownership of Northvolt Dwa ESS, Europe’s largest energy storage systems manufacturing operation, located in Gdansk, Poland. Lyten intends to immediately restart production in Gdansk to resume sales of battery energy storage systems (BESS) and is expanding its product line to include the world’s first BESS powered by lithium-sulfur batteries. This complements Lyten’s previously announced acquisition of Northvolt’s lithium-metal cell manufacturing facility in Silicon Valley to scale its lithium-sulfur battery production. Lyten, the supermaterial applications company and global leader in lithium-sulfur batteries, announced today the acquisition of Northvolt’s Dwa ESS operations in Gdansk, Poland, a 25,000 square meter (270,000 sq ft) battery energy storage systems (BESS) manufacturing and R&D facility. Northvolt Dwa ESS is the largest BESS manufacturing facility in Europe and was part of Northvolt Systems. The financial terms of the acquisition are not being released
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom