BIOCYTOGEN
Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (“Biocytogen”, HKEX: 02315) today announces an antibody evaluation and option agreement with Gilead Sciences, Inc. The agreement provides Gilead access to Biocytogen’s extensive fully human antibody library generated against a wide range of therapeutic targets. Over a three-year nomination period, Gilead will nominate targets of interest and evaluate the corresponding antibodies, with the option to acquire selected antibodies for worldwide therapeutic development.
Under the terms of the agreement, Biocytogen will receive a payment to enable Gilead’s evaluation of certain antibodies directed to a given nominated target. Biocytogen is eligible to receive option exercise fees along with development, regulatory and sales milestone payments for each selected antibody against the nominated targets, as well as single-digit royalties on net sales.
Dr. Yuelei Shen, President and CEO of Biocytogen, said, “We are thrilled to collaborate with Gilead, a partner renowned for their drug development and commercialization expertise. Our extensive library of RenMice®-derived, fully human antibodies could serve as an important resource for Gilead to accelerate development of multiple novel antibody-based therapeutics to treat a variety of diseases. We are committed to supporting Gilead as well as our other partners in their drug development endeavors to benefit patients.”
About Biocytogen’s Fully Human Antibody Library
Biocytogen’s antibody library was generated using a series of proprietary RenMice® platforms, which were genetically engineered to accelerate the development of novel antibody-based therapeutics. RenMabTM mice carry the entire human antibody variable region repertoire, and can generate fully human antibodies with high diversity, low immunogenicity, outstanding specificity and affinity, and exhibit excellent developability properties. Second-generation RenLite® and RenNano® models, which generate common light chain antibodies and heavy-chain-only antibodies, respectively, further facilitate generation of fully human multi-specific antibodies or nanobodies. RenMice have also been engineered to lack specific drug targets; these targeted knockout platforms can generate antibodies with enhanced sequence and epitope diversity. This platform increases the likelihood of discovering novel species cross-reactive antibodies to facilitate downstream in vivo screening and identification of differentiated antibody candidates. A library featuring available antibody sequences along with characterization data is ready for immediate evaluation and partnership opportunities.
About Biocytogen
Biocytogen (HKEX: 02315) is a global biotechnology company that drives the research and development of novel antibody-based drugs with innovative technologies. Founded on gene editing technology, Biocytogen leverages genetically engineered proprietary RenMice® (RenMabTM/RenLite®/RenNano®/RenTCR-mimicTM) platforms for fully human monoclonal/bispecific/multispecific antibody discovery, bispecific antibody-drug conjugate discovery, nanobody discovery and TCR-mimic antibody discovery, and has established an off-the-shelf library of >400,000 fully human antibody sequences against approximately 1000 targets for worldwide collaboration. As of June 30, 2023, 50 therapeutic antibody and multiple clinical asset co-development/out-licensing/transfer agreements and 42 target-nominated RenMice® licensing projects have been established around the globe, including several partnerships with multinational pharmaceutical companies (MNCs). Biocytogen pioneered the generation of drug target knock-in humanized models for preclinical research, and currently provides a few thousand off-the-shelf animal and cell models under the company’s sub-brand, BioMiceTM, along with preclinical pharmacology and gene-editing services for clients worldwide. Headquartered in Beijing, Biocytogen has branches in China (Haimen Jiangsu, Shanghai), USA (Boston, San Francisco), and Germany (Heidelberg). For more information, please visit http://en.biocytogen.com.cn.
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
View source version on businesswire.com: https://www.businesswire.com/news/home/20240220445787/en/
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Mesmerise to collaborate with Mayo Clinic to Transform Medical Education and Healthcare Workforce Training13.1.2025 23:10:00 CET | Press release
Mesmerise is proud to announce the creation of NeuRealities, Inc., a transformative company designed to revolutionize medical education and healthcare training. As part of a know-how agreement with Mayo Clinic, the new company seeks to leverage Mayo Clinic’s unparalleled clinical expertise and trusted knowledge with Mesmerise’s pioneering advancements in AI-powered spatial computing to set a new standard for excellence in immersive learning experiences. NeuRealities aims to introduce an open-standards digital platform that redefines how healthcare professionals learn and train. By integrating hyper-realistic AI-enabled digital humans, adaptive immersive experiences, and dynamic content tailored to individual learners, the platform can address critical gaps in medical education. Its first initiative—CT training for radiologic technicians—delivers interactive, hands-on scenarios that simplify complex medical concepts, allowing the potential for training to be more efficient, accessible,
Jefferies to Hold Global Trading Day on January 16 to Support Los Angeles Wildfire Relief Efforts13.1.2025 22:15:00 CET | Press release
Jefferies announced today that it will hold a Global Trading Day on January 16, 2025, to raise funds for organizations supporting first responders and those impacted by the fires. Jefferies will donate 100% of net global commissions on January 16 for all trading in equities and fixed income by the Firm’s clients. Jefferies will also make a $1 million donation and encourage its nearly 6,000 employees to personally support relief efforts. During the month following this Global Trading Day, contributions will be carefully allocated to qualified charities to ensure the proceeds go directly to support the people and communities most in need. Rich Handler, CEO, and Brian Friedman, President of Jefferies, said: “We are heartbroken by the wildfires causing unfathomable destruction in the Los Angeles area. Our firm was founded in Los Angeles 62 years ago, and it has always been a resilient community, full of dynamism, opportunity and strength. Our hearts go out to all those affected, and we sta
AEM Launches WMO-Compliant Automated Weather Station to Elevate Global Weather Monitoring13.1.2025 16:00:00 CET | Press release
AEM, the essential source for environmental insights, today announced its WMO-compliant AEM Apex Automated Weather Station (AWS). This state-of-the-art solution sets a new benchmark for precision, reliability, and durability, meeting the strict standards of the World Meteorological Organization (WMO). Designed to address the toughest challenges in weather monitoring, the WMO-compliant AWS offers unparalleled accuracy and performance for a variety of critical applications, from localized climate research to large-scale weather networks. Key Benefits of the WMO-Compliant AWSPrecision Data for Better Decisions: Provides WMO-compliant measurements with strict tolerances to support critical applications. Seamless Global Collaboration: Enables efficient data sharing with regional and global partners, fostering enhanced coordination for monitoring and forecasting. Reliability in Extreme Conditions: Built to deliver continuous, accurate data with minimal maintenance, even in the most demanding
Greenland Resources Signs Advisory Agreement With Rasmussen Global on Defense13.1.2025 15:30:00 CET | Press release
Greenland Resources Inc. (Cboe CA: MOLY | FSE: M0LY) “Greenland Resources” or the “Company”) is pleased to announce that it has signed an advisory agreement with Rasmussen Global to complement the Malmbjerg Project existing funding strategy through potential strategic supranational partners, including the North Atlantic Treaty Organization (NATO) Innovation Fund and the European Defense Fund. Rasmussen Global was founded and is chaired by Anders Fogh Rasmussen, the former Prime Minister of Denmark and former Secretary General of NATO. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250113410398/en/ The Project is strategically located in east central Greenland and based on its current NI 43-101 Feasibility Study, can supply some 25% of the European Union (EU) total molybdenum consumption for decades to come including nearly all the EU defense needs. Currently, the EU is the 2nd largest molybdenum user in the world and has no
Starr Names Peter Hirs to Succeed Howard Smith as CFO13.1.2025 15:30:00 CET | Press release
Starr announced that Peter Hirs has been named the company’s chief financial officer, effective January 13, succeeding Howard I. Smith, who is retiring after more than 40 years at Starr and related entities. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250113071409/en/ Peter Hirs, chief financial officer, Starr (Photo: Business Wire) Hirs brings significant finance and insurance experience to Starr, having spent the past 20 years at a global insurance carrier, where he managed regional finance teams across the world and led mergers and acquisitions activities. In his new role, Hirs will oversee the organization’s global finance operations. He is based at Starr’s head office in New York. Smith had led Starr’s financial operations since 2005, when Maurice R. “Hank” Greenberg, Starr’s chairman emeritus, re-established Starr as a free-standing investment and insurance organization, and he worked closely with Hank prior to that
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom