MEIJI-SEIKA-PHARMA/FBRI
Meiji Seika Pharma Co., Ltd. (Headquarters: Tokyo, Japan, President and Representative Director: Daikichiro Kobayashi) and the Foundation for Biomedical Research and Innovation at Kobe (Headquarters: Kobe, Japan, President: Tasuku Honjo, hereinafter ‘FBRI’) announce the discovery of a novel anti-PD-1 agonist monoclonal antibody, which can induce immunosuppressive effect, through their collaborative research on “Treatment of inflammatory diseases, including autoimmune diseases, through the immunosuppressive activity of PD-1” (HBI* Innovation Program) conducted at the FBRI's Dept. of Immunology, Institute of Biomedical Research and Innovation (Professor: Akio Ohta). Part of the findings from the above research was published in "Science Immunology**" issued on January 13, 2023 (Eastern Standard Time). For more information, please visit the FBRI website (URL: https://www.fbri-kobe.org/kbic/english/pressrelease/2023_01-16/).
Meiji Seika Pharma and FBRI are working together to develop the above PD-1 agonist monoclonal antibody as therapeutic candidate for autoimmune diseases.
PD-1 is a molecule expressed on activated lymphocytes and has the function as a suppressor of immune responses. Antibodies that inhibit the function of PD-1 (anti-PD-1 blocking antibodies) can enhance anti-tumor immunity, so that they have been applied to cancer treatment as "immune checkpoint inhibitors."
Through the above joint research supervised by Program Director Tasuku Honjo, Nobel laureate in 2018, Meiji Seika Pharma and FBRI discovered the conditions necessary for inducing immunosuppression by stimulating the function of PD-1 with antibodies. "Anti-PD-1 agonist antibody" is expected to be applied as a novel therapeutic for inflammatory diseases such as autoimmune diseases caused by excessive immune reactions.
Meiji Seika Pharma and FBRI continue to progress the joint research on "anti-PD-1 agonist antibody" and strive to the early contribution of this antibody as a therapeutic agent for autoimmune diseases.
*: HBI: Honjo Kobe Research Center for Biomedical Innovation
**: DOI: 10.1126/sciimmunol.add4947
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
View source version on businesswire.com: https://www.businesswire.com/news/home/20230115005001/en/
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
TriLink BioTechnologies® and Aldevron Enter into Non-exclusive License and Supply Agreement for CleanCap® mRNA Capping Technology4.2.2025 22:01:00 CET | Press release
Enabling the future development of critical therapeutics, Aldevron customers now have access to TriLink’s CleanCap mRNA capping technology for non-commercial use TriLink BioTechnologies (TriLink®), a Maravai® LifeSciences company (NASDAQ: MRVI) and global provider of life science reagents and services, has signed a non-exclusive License and Supply Agreement with Aldevron, a leading, global Contract Development and Manufacturing Organization (CDMO) providing high-quality plasmid DNA, RNA, and proteins for research, therapeutics, and diagnostics. With this agreement with Aldevron, TriLink strengthens its objective to provide greater access to CleanCap® mRNA capping technologies to those developing critical mRNA-based therapeutics and vaccines. According to the terms of the agreement, TriLink will supply its patented CleanCap® M6, CleanCap® AG 3’OMe, CleanCap® AG, and CleanCap® AU cap analogs for use in Aldevron’s mRNA development and manufacturing services, from pre-clinical through Phas
Telcoin Granted Approval to Open Nebraska’s First Digital Asset Bank4.2.2025 20:32:00 CET | Press release
Regulators give green light for first regulated bank explicitly authorized to connect US consumers to decentralized finance, ushering in a new era of blockchain-integrated banking. Telcoin, a pioneer in blockchain-based financial services, announced that its application to become Nebraska’s first Digital Asset Depository Institution has been conditionally approved by the state’s Department of Banking and Finance. This approval brings Telcoin Bank, a Digital Asset Bank, another step closer to creating the first real bridge between traditional finance and cryptocurrencies. Telcoin Bank is now poised to become the first regulated crypto bank in the United States. Its upcoming launch is expected to disrupt the US$200 billion stablecoin market and transform the financial landscape by offering fully regulated, bank-issued “Digital Cash” stablecoins, as well as an innovative suite of blockchain banking products and services. This development promises to accelerate the adoption of crypto in ma
HTEC and AI Inference Hardware Startup, d-Matrix, Announce Strategic Partnership4.2.2025 19:23:00 CET | Press release
HTEC, a global consulting, software, and digital product development company, is proud to announce a strategic partnership with d-Matrix, the creator of Corsair™, the world’s most efficient AI computing platform for inference in datacenters. HTEC Advisory Board member Sasha Ostojic, who also sits on d-Matrix's Board of Directors, was instrumental in connecting the companies and expediting the collaboration. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250204571709/en/ HTEC announces partnership with d-Matrix, the creator of Corsair™, the world’s most efficient AI computing platform for inference in datacenters (Graphic: Business Wire) During their work together, HTEC will leverage its extensive expertise in AI and embedded software development to support d-Matrix in the development of its software solution. Additionally,HTEC will use an active management approach to proactively identify and address issues and robust report
Monroe Capital Hires Galen Fu as Director, Business Development and Opens Australia Office4.2.2025 17:00:00 CET | Press release
Monroe Capital LLC (“Monroe”) today announced it has expanded its platform to Australia with the appointment of Galen Fu as Director, Business Development. Fu will be based in the firm’s Sydney, Australia office and will be responsible for client servicing and capital raising across Australia. Fu has more than 14 years of experience in capital raising, portfolio management and banking in the Asia-Pacific region. Prior to Monroe, he was a Director in the Capital Markets team at Hines Investment Management where he was responsible for business development and investor relations across Australia. He previously held roles at MaxCap Investment Management (a subsidiary of Apollo Global Management), Westpac Bank and ANZ Bank. Fu earned his B.A. in Commerce and Economics from the University of New South Wales. “We have several long-standing limited partners in Australia and we look forward to our continued strategic growth and expansion in Australia,” said Zia Uddin, President of Monroe Capita
NTT DATA, Inc. Appoints Sudhir Chaturvedi as Global Chief Growth Officer and North America CEO4.2.2025 17:00:00 CET | Press release
NTT DATA, a global digital business and IT services leader, today announced that Sudhir Chaturvedi will join NTT DATA, Inc. as its Global Chief Growth Officer and North America Chief Executive Officer. In the newly created Global Chief Growth Officer role, Chaturvedi will lead the acceleration of consistent growth strategies globally, with special focus on global industries, strategic accounts, and joint go-to-market execution with key strategic partners. In his North America CEO role, Chaturvedi will lead NTT DATA Inc.’s growth and business in this strategic region, while leveraging synergies with his Global Chief Growth Officer remit. Chaturvedi succeeds Eric Clark who is leaving the company for a leadership role outside of NTT DATA. Chaturvedi will report to Abhijit Dubey, President and Global CEO of NTT DATA, Inc., and plans to be based in Plano, TX. “Sudhir has a unique blend of expertise across Consulting, IT Services and Software, alongside industry, digital transformation and s
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom