INOTREM
Inotrem, an advanced clinical stage biotech company specialized in immunotherapies for acute and chronic inflammatory syndromes, announced today it received funding from the Crohn’s & Colitis Foundation’s IBD Ventures under a program to accelerate research and development that aim to improve the quality of life for patients with IBD. The funding will support the development of a new therapeutic approach in IBD focusing on the TREM-1 pathway.
The funding follows a R&D collaboration between Inotrem, and the Crohn’s & Colitis Foundation announced in April 2022. The R&D collaboration seeks to pave the way of a personalized medicine approach in IBD patients based on TREM-1. Under the terms of the agreement, Inotrem has access to data and bio-samples from Foundation’s IBD Plexus®, which is the largest IBD database in the US with data from over 25,000 patients. Lasting over 18 months, the project will be a cornerstone in the design of Inotrem’s first-in-human clinical study with INO-02.
There are today 10 million people worldwide suffering from IBD, and the need for new therapeutic options remains very strong. Approximately 30% of patients are unresponsive to existing therapies and even among the initial responders, in up to 10% the drugs lose efficacy over time. For a decade, Inotrem has been elucidating the biology of TREM-1 as a regulator of the immune response in both acute as well as chronic inflammatory diseases. TREM-1 is a potential important contributor to IBD pathophysiology and targeting this pathway may offer a new treatment option for IBD patients with immune dysregulation.
“We are grateful for the support of such a well-respected organization as The Crohn’s & Colitis Foundation. This funding will help us to expand our patented technology platform centered around the TREM-1 pathway and dedicated to developing new therapies for chronic inflammatory syndromes next to our existing modalities for acute diseases,” indicates Sven Zimmermann, CEO of Inotrem.
“Beyond the financial support, this is a strong recognition of Inotrem’s scientific leadership regarding the role of the TREM-1 pathway in inflammatory processes as well as our robust therapeutic approaches targeting that biological target,” says Marc Derive, Chief Scientific Officer and Cofounder of Inotrem.
About Inotrem
Inotrem S.A. is an advanced clinical stage biotech company specialized in immunotherapies for acute and chronic inflammatory syndromes. The company has developed a new concept of immunomodulation that targets the TREM-1 pathway to control unbalanced inflammatory responses. Through its proprietary technology platform, Inotrem has developed the first-in-class TREM-1 inhibitor, nangibotide, with potential applications in a number of therapeutic indications such as septic shock and myocardial infarction. In parallel, Inotrem has also launched another program to develop a new therapeutic modality targeting chronic inflammatory diseases. The company was founded in 2013 by Dr Jean-Jacques Garaud, a former head of research and early development at the Roche Group, Prof. Sebastien Gibot and Dr Marc Derive. Inotrem is supported by leading European and North American investors. www.inotrem.com
About the Crohn’s & Colitis Foundation
The Crohn's & Colitis Foundation is the leading non-profit organization focused on both research and patient support for inflammatory bowel disease (IBD), with the mission of curing Crohn's disease and ulcerative colitis, and of improving the quality of life of the millions of Americans living with IBD. The Foundation’s work is dramatically accelerating the research process through investment in research initiatives, while also providing extensive educational and support resources for patients and their families, medical professionals, and the public. For more information, visit crohnscolitisfoundation.org, call 888-694-8872, or email info@crohnscolitisfoundation.org.
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
View source version on businesswire.com: https://www.businesswire.com/news/home/20230109005241/en/
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Tageos and Wiliot Partner to Accelerate Ambient IoT, Battery-Free BLE Sensing22.1.2026 16:07:00 CET | Press release
Strategic partnership unlocks latest advancements from Tageos’ Innovation Center of Excellence, starting with the battery-free EOS-654 BLE G3 inlay for Wiliot’s Gen3 IoT Pixel sensor and the Wiliot Intelligence Platform Tageos, a global leader in RFID and wireless IoT inlays and tags, today announced a strategic partnership with ambient IoT pioneer Wiliot. The first outcome of this collaboration is the launch of a new passive Bluetooth® Low Energy (BLE) inlay, the EOS-654 BLE G3. In response growing demand for real-time location and condition monitoring across retail and logistics supply chains, this inlay was developed to support large-scale deployment of Wiliot’s Gen3 IoT Pixel sensor and the Wiliot Intelligence Platform. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260122940104/en/ The new EOS-654 BLE G3 features a dual-band architecture operating at 2.4 GHz and sub-1 GHz. This inlay design enables longer-range energizi
ForecastEx Appoints Renowned Forecaster Dr. Philip Tetlock to Board of Directors22.1.2026 16:00:00 CET | Press release
ForecastEx Strengthens Commitment to Predictive Excellence and Market Innovation Interactive Brokers (Nasdaq: IBKR), an automated global electronic broker, announced the appointment of Dr. Philip Tetlock to the Board of Directors of ForecastEx. Dr. Tetlock is internationally recognized for his groundbreaking expertise in forecasting, probability-based judgment, and decision-making under uncertainty, which closely aligns with ForecastEx’s prediction market model. His presence on the Board strengthens ForecastEx’s governance and regulatory oversight, adding subject-matter expertise relevant to market integrity, risk management, and outcome resolution. Thomas Peterffy, Founder and Chairman of Interactive Brokers, stated: “We are pleased to welcome Dr. Philip Tetlock to the Board of Directors of ForecastEx. Prediction markets are founded on the uncertainty of the future and the probabilities associated with potential outcomes. By aggregating consensus probabilities, forecast contracts can
Rimini Street Delivers First 20 Rimini Agentic UX™ Solutions That Solve a Variety of ERP Process Challenges Faster, Better and Cheaper with Agentic AI ERP22.1.2026 15:00:00 CET | Press release
Rimini Agentic UX™ Solutions, Powered by ServiceNow®, deliver enhanced productivity, greater agility and reduced operating cost while being quick, easy and economical to deploy over the top of existing ERP Software releases without any required upgrades or migrations Rimini Street, Inc. (Nasdaq: RMNI), the Software Support and Agentic AI ERP Company™, and the leading third-party support provider for Oracle, SAP and VMware software, today announced the immediate availability of its first 20 innovative Rimini Agentic UX™ Solutions, Powered by ServiceNow®. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260122013155/en/ Rimini Street Delivers First 20 Rimini Agentic UX™ Solutions That Solve a Variety of ERP Process Challenges Faster, Better and Cheaper with Agentic AI ERP Solving Real Business Challenges Now with Agentic AI ERP Rimini Agentic UX Solutions are already in production and helping organizations achieve better busines
LoungePair Brings on Former LoungeBuddy CEO, Enters Agreements with Vietnam Airlines, Auckland Airport22.1.2026 15:00:00 CET | Press release
Travel-tech company LoungePair has brought on LoungeBuddy founder and former American Express executive Tyler Dikman as a key advisor. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260122515067/en/ Tyler Dikman, joins LoungePair as Key Advisor The company has also signed a key partnership with Vietnam Airlines to power its new Lotusmiles Lounges platform and has added Auckland Airport's Strata Lounge to its network. LoungePair provides on-demand and walk-up airport lounge access without the need for additional memberships, reward programmes, or loyalty status. Travel Tech Expert Tyler Dikman Joins as Advisor Tyler Dikman is the co-founder and former CEO of LoungeBuddy, the airport lounge booking platform acquired by American Express in 2019. Following the acquisition, he served as Vice President of Global Premium Products and Benefits at American Express, leading the integration of LoungeBuddy and helping shape travel exper
Lone Star Acquires Alliance Ground International22.1.2026 14:55:00 CET | Press release
Lone Star Funds (“Lone Star”) today announced that an affiliate of Lone Star Fund XII, L.P. has entered into a definitive agreement to acquire Alliance Ground International (“AGI”), a leading North American airport services provider, from Greenbriar Equity Group and Audax Private Equity. Financial terms of the transaction were not disclosed. Founded in 1987 and headquartered in Miami, AGI operates in over 60 airports in North America with a workforce of more than 12,000 professionals. The company provides mission-critical, outsourced services that enable the efficient movement of cargo and passenger aircraft through major airport hubs. AGI’s core business is air cargo handling, supported by passenger terminal, ground handling and other related services. Its integrated service offering, strategic on-airport footprint and long-standing customer relationships position AGI as a trusted partner to cargo carriers and passenger airlines, supporting airport operations and global trade flows. L
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.
Visit our pressroom