326 Søgeresultatclinical

LEO Pharma

LEO Pharma Presents New Late-Breaking Delgocitinib Cream Data For the Third Consecutive Year at AAD 20258.3.2025 17:45:38 CET | LEO Pharma | Pressemeddelelse

The post hoc analysis investigated treatment responses in a patient subgroup with moderate to severe Chronic Hand Eczema (CHE) treated with delgocitinib cream for 16 weeks in the DELTA 1 2 phase 3 trials.(1) Late-breaking presentation showcased that delgocitinib cream produced a deep, consistent and/or maintained response in a subgroup of patients with moderate to severe Chronic Hand Eczema (CHE).(1) Separate data presented at the American Academy of Dermatology (AAD) 2025 Annual Meeting evaluated systemic exposure in patients following high use of delgocitinib cream to treat moderate to severe CHE.(2)
Københavns Universitet      -        Det Natur- og Biovidenskabelige Fakultet

New Research: Strong Link Between Western Diet During Pregnancy and ADHD4.3.2025 09:40:09 CET | Københavns Universitet - Det Natur- og Biovidenskabelige Fakultet | Pressemeddelelse

New research from Denmark reveals that a mother’s diet during pregnancy—characterised by a Western dietary pattern high in fat and sugar and low in fresh ingredients—may increase the risk of neurodevelopmental disorders such as ADHD and autism in children. Researchers see potential for targeted dietary interventions during pregnancy to reduce this risk.
Københavns Universitet – Institut for Idræt og Ernæring

Mindre kulhydrat og mere protein og fedt mindsker risikofaktorer for hjertekarsygdomme ved type 2-diabetes19.2.2025 10:10:00 CET | Københavns Universitet – Institut for Idræt og Ernæring | Pressemeddelelse

Forskning viser, at en reduceret mængde kulhydrat og en øget mængde protein og fedt i kosten nedsætter fedtindholdet i leveren og blodet hos personer med type 2-diabetes. Hermed reduceres risikofaktorer for udvikling af hjertekarsygdomme og sygdom i leveren. Forbedringerne er uafhængige af, om man taber sig i vægt. Sådan lyder konklusionerne fra et nyt studie udført på Bispebjerg Hospital og Institut for Idræt og Ernæring ved Københavns Universitet.

DEBRA Research and LEO Pharma Announce Strategic Partnership to Advance Treatments for Rare Skin Diseases5.2.2025 09:00:00 CET | LEO Pharma | Pressemeddelelse

Partners form non-exclusive collaboration to expand research efforts and develop new treatments for Epidermolysis Bullosa (EB). The partnership leverages DEBRA Research’s focus on patient care and pharma experience and LEO Pharma’s extensive medical dermatology experience. Munich, Germany, and Ballerup, Denmark, 5 February 2025 – DEBRA Research GmbH, a non-profit organization dedicated to advancing research, advocacy, and support for those affected by Epidermolysis Bullosa (EB) and LEO Pharma, a global leader in medical dermatology, today announced a non-exclusive strategic partnership. This collaboration aims to enhance scouting capabilities and provide additional capacity to accelerate the development of life-changing therapies for EB. The partners are committed to driving transformative progress for EB patients and their families, and to deliver innovative medicines for this serious skin disease with no approved treatment options. “We are pleased to announce our non-exclusive partne
LEO Pharma

LEO Pharma Achieves Positive DELTA TEEN Trial Results with Anzupgo® (delgocitinib) Cream in Adolescents with Moderate to Severe Chronic Hand Eczema (CHE)4.2.2025 14:00:00 CET | LEO Pharma | Pressemeddelelse

The phase 3 clinical trial (DELTA TEEN) with Anzupgo® in adolescents, aged 12-17, with moderate to severe Chronic Hand Eczema (CHE) for whom topical corticosteroids are inadequate or inappropriate, achieved primary and all key secondary endpoints compared to cream vehicle.(1) CHE can significantly affect the quality of life for adolescent patients.(2) There are currently no approved treatment options specifically indicated for moderate to severe CHE in the adolescent patient population.

LTS wins funding from BARDA’s Patch Forward Prize Competition for two partnerships14.1.2025 13:21:17 CET | LTS Lohmann Therapie-Systeme AG | Press release

Andernach – LTS LOHMANN Therapie-Systeme AG (“LTS”), a leading pharmaceutical technology company, is proud to announces its selection as a Concept Stage winner for two projects in the #PatchForwardPrize, a $50 million challenge by the Biomedical Advanced Research and Development Authority (BARDA) to advance microneedle patch-based RNA vaccine technologies.
LEO Pharma

LEO Pharma’s Anzupgo® (delgocitinib) Cream Achieves Marketing Approval in Switzerland14.11.2024 10:31:50 CET | LEO Pharma | Pressemeddelelse

The Swiss Agency for Therapeutic Products, Swissmedic, has approved Anzupgo®, making it the first topical pan-Janus kinase (JAK) inhibitor specifically indicated for the treatment of moderate to severe Chronic Hand Eczema (CHE) in adults who have had an inadequate response to topical corticosteroids, or for whom potent to very potent topical corticosteroids are not advisable.(1) The approval will bring a new treatment option to approximately 4.7% of adults in Switzerland living with CHE, a condition with a high unmet need for which no specifically approved topical treatment was previously available.(2,3) In addition to the results of the DELTA 1,2 and 3 trials, the marketing approval is supported by the head-to-head DELTA FORCE trial of Anzupgo against oral alitretinoin capsules, the only other existing specifically approved treatment for severe CHE.(4-7)
Grünenthal Group

Grünenthal and Averitas Pharma announce completion of recruitment for Phase III clinical trial with QUTENZA® in post-surgical neuropathic pain7.11.2024 11:26:47 CET | Grünenthal Group | Press release

The Phase III trial AV001 aims to evaluate QUTENZA® in post-surgical neuropathic pain (PSNP), a debilitating complication of surgery occurring after approximately 10 percent of all surgical procedures[1], thus affecting more than 3 million people with surgical procedures per year in the U.S.[2] QUTENZA® is a topical system, non-systemic, non-opioid pain treatment that is currently approved in the US for the treatment of neuropathic pain associated with postherpetic neuralgia (PHN) and neuropathic pain associated with diabetic peripheral neuropathy (DPN) of the feet in adults. Topline results are expected in Q4 2025 and Averitas Pharma aims to submit a supplemental new drug application (sNDA) for a US label extension in 2026, subject to positive data.
LEO Pharma

LEO Pharma lancerer Anzupgo® (delgocitinib) creme i hjemmemarkedet Danmark som det andet land i verden28.10.2024 12:00:00 CET | LEO Pharma | Pressemeddelelse

Efter Europa Kommissionens produktgodkendelse i september bliver Danmark det næste og kun andet land i verden, hvor LEO Pharma lancerer sit nyeste lægemiddel, Anzupgo® (delgocitinib) creme, efter lanceringen i Tyskland tidligere på måneden. (1) Anzupgo® creme er den første godkendte topikale behandling for voksne med moderat til svært kronisk håndeksem, hvor topikale kortikosteroider er utilstrækkelige eller uhensigtsmæssige. (1) Lanceringen giver en ny behandlingsmulighed for de mange voksne danskere, som lever med moderat til svært kronisk håndeksem, som er en af de mest udbredte kroniske inflammatoriske hudsygdomme, der rammer 4,7% af befolkningen. (2,3)
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